Literature DB >> 22644845

Bioactive cadinane-type compounds from the soft coral Sinularia scabra.

Jui-Hsin Su1, Chiung-Yao Huang, Po-Ju Li, Yi Lu, Zhi-Hong Wen, Yao-Haur Kao, Jyh-Horng Sheu.   

Abstract

Two new cadinane-type sesquiterpenoids, scabralins A (1) and B (2) were obtained from the soft coral Sinularia scabra. Metabolite 1 was shown to exhibit moderate to weak cytotoxicity against MCF-7, WiDr, Daoy, and HEp 2 cancer cell lines. Also, incubation with 10 µM compound 1 significantly inhibited the accumulation of the pro-inflammatory inducible nitric oxide synthase protein in lipopolysaccharide-stimulated RAW264.7 macrophage cells.

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Year:  2012        PMID： 22644845     DOI： 10.1007/s12272-012-0503-2

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  8 in total

Review 1.  Anti-inflammatory activities of natural products isolated from soft corals of Taiwan between 2008 and 2012.

Authors:  Wen-Chi Wei; Ping-Jyun Sung; Chang-Yih Duh; Bo-Wei Chen; Jyh-Horng Sheu; Ning-Sun Yang
Journal:  Mar Drugs       Date:  2013-10-23       Impact factor: 5.118

Review 2.  Coral and Coral-Associated Microorganisms: A Prolific Source of Potential Bioactive Natural Products.

Authors:  Vo Thanh Sang; Ton That Huu Dat; Le Ba Vinh; Le Canh Viet Cuong; Phung Thi Thuy Oanh; Hoang Ha; Young Ho Kim; Hoang Le Tuan Anh; Seo Young Yang
Journal:  Mar Drugs       Date:  2019-08-11       Impact factor: 5.118

3.  Marine Invertebrate Extracts Induce Colon Cancer Cell Death via ROS-Mediated DNA Oxidative Damage and Mitochondrial Impairment.

Authors:  Verónica Ruiz-Torres; Celia Rodríguez-Pérez; María Herranz-López; Beatriz Martín-García; Ana-María Gómez-Caravaca; David Arráez-Román; Antonio Segura-Carretero; Enrique Barrajón-Catalán; Vicente Micol
Journal:  Biomolecules       Date:  2019-11-23

Review 4.  Cytotoxic Compounds from Alcyoniidae: An Overview of the Last 30 Years.

Authors:  Federico Cerri; Francesco Saliu; Davide Maggioni; Simone Montano; Davide Seveso; Silvia Lavorano; Luca Zoia; Fabio Gosetti; Marina Lasagni; Marco Orlandi; Orazio Taglialatela-Scafati; Paolo Galli
Journal:  Mar Drugs       Date:  2022-02-11       Impact factor: 5.118

5.  A soft coral-derived compound, 11-epi-sinulariolide acetate suppresses inflammatory response and bone destruction in adjuvant-induced arthritis.

Authors:  Yen-You Lin; Yen-Hsuan Jean; Hsin-Pai Lee; Wu-Fu Chen; Yu-Min Sun; Jui-Hsin Su; Yi Lu; Shi-Ying Huang; Han-Chun Hung; Ping-Jyun Sung; Jyh-Horng Sheu; Zhi-Hong Wen
Journal:  PLoS One       Date:  2013-05-13       Impact factor: 3.240

6.  Marine Peroxy Sesquiterpenoids Induce Apoptosis by Modulation of Nrf2-ARE Signaling in HCT116 Colon Cancer Cells.

Authors:  Junsei Taira; Haruna Miyazato; Katsuhiro Ueda
Journal:  Mar Drugs       Date:  2018-09-23       Impact factor: 5.118

Review 7.  Different Macrophage Type Triggering as Target of the Action of Biologically Active Substances from Marine Invertebrates.

Authors:  Lyudmila S Dolmatova; Igor Yu Dolmatov
Journal:  Mar Drugs       Date:  2020-01-02       Impact factor: 5.118

8.  Isolation of Sesquiterpenoids and Steroids from the Soft Coral Sinularia brassica and Determination of Their Absolute Configuration.

Authors:  Giang Nam Pham; Da Yeun Kang; Min Ju Kim; Se Jong Han; Jun Hyuck Lee; MinKyun Na
Journal:  Mar Drugs       Date:  2021-09-17       Impact factor: 5.118
  8 in total

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