Literature DB >> 22641987

Elevated troponin T levels in a female carrier of Duchenne muscular dystrophy with normal coronary angiogram: a case report and review of the literature.

Jan De Pooter1, Joke Vandeweghe, An Vonck, Peter Loth, Joost Geraedts.   

Abstract

We present the case of a 48-year-old female carrier of Duchenne muscular dystrophy (DMD) with repeatedly documented levels of elevated troponin T without arguments for cardiac ischaemia. Elevated levels of troponin T are frequently reported in DMD patients and may function as a useful cardiac index to assess dystrophic degeneration of the myocardium in a subclinical stage. Cardiac troponins may help the clinician to diagnose myocardial damage in a very early stage of cardiac impairment independently from skeletal muscle degeneration.

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Year:  2012        PMID: 22641987     DOI: 10.1080/ac.67.2.2154220

Source DB:  PubMed          Journal:  Acta Cardiol        ISSN: 0001-5385            Impact factor:   1.718


  5 in total

1.  Troponin I Levels Correlate with Cardiac MR LGE and Native T1 Values in Duchenne Muscular Dystrophy Cardiomyopathy and Identify Early Disease Progression.

Authors:  Sonia Voleti; Laura Olivieri; Karin Hamann; Heather Gordish-Dressman; Christopher Spurney
Journal:  Pediatr Cardiol       Date:  2020-05-31       Impact factor: 1.655

2.  Dystrophin-deficient cardiomyocytes derived from human urine: new biologic reagents for drug discovery.

Authors:  Xuan Guan; David L Mack; Claudia M Moreno; Jennifer L Strande; Julie Mathieu; Yingai Shi; Chad D Markert; Zejing Wang; Guihua Liu; Michael W Lawlor; Emily C Moorefield; Tara N Jones; James A Fugate; Mark E Furth; Charles E Murry; Hannele Ruohola-Baker; Yuanyuan Zhang; Luis F Santana; Martin K Childers
Journal:  Stem Cell Res       Date:  2013-12-23       Impact factor: 2.020

3.  Muscular and cardiac manifestations in a Duchenne-carrier harboring a dystrophin deletion of exons 12-29.

Authors:  Josef Finsterer; Claudia Stöllberger; Birgit Freudenthaler; Desiree De Simoni; Romana Höftberger; Klaus Wagner
Journal:  Intractable Rare Dis Res       Date:  2018-05

4.  Elevated plasma levels of cardiac troponin-I predict left ventricular systolic dysfunction in patients with myotonic dystrophy type 1: A multicentre cohort follow-up study.

Authors:  Mark J Hamilton; Yvonne Robb; Sarah Cumming; Helen Gregory; Alexis Duncan; Monika Rahman; Anne McKeown; Catherine McWilliam; John Dean; Alison Wilcox; Maria E Farrugia; Anneli Cooper; Josephine McGhie; Berit Adam; Richard Petty; Cheryl Longman; Iain Findlay; Alan Japp; Darren G Monckton; Martin A Denvir
Journal:  PLoS One       Date:  2017-03-21       Impact factor: 3.240

Review 5.  Current state of cardiac troponin testing in Duchenne muscular dystrophy cardiomyopathy: review and recommendations from the Parent Project Muscular Dystrophy expert panel.

Authors:  Christopher F Spurney; Deborah Ascheim; Lawrence Charnas; Linda Cripe; Kan Hor; Nicholas King; Kathi Kinnett; Elizabeth M McNally; John-Michael Sauer; Lee Sweeney; Chet Villa; Larry W Markham
Journal:  Open Heart       Date:  2021-03
  5 in total

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