Literature DB >> 22641930

Disability in a community population with MS with and without mental disorders.

Scott B Patten1, Jeanne V A Williams, Dina H Lavorato, Luanne M Metz, Andrew G M Bulloch.   

Abstract

OBJECTIVE: Psychiatric conditions are known to have a detrimental impact on functioning and may therefore influence patterns of disability associated with MS. Population-based studies are needed to evaluate such interactions. The objective of this study was to describe the pattern of interaction of MS and mental disorders on health-related impairments.
METHODS: The Participation and Activity Limitation Survey (PALS) was a post-censual survey conducted by Statistics Canada in association with the 2006 Canadian Census. PALS collected detailed data from a random sample of n = 28,640 respondents with health-related impairments reported on their census form. The PALS interview collected self-reported diagnostic data and included scales to assess functioning and participation in society.
RESULTS: PALS identified 245 individuals with MS, leading to an estimated (weighted) population prevalence of 0.2% (200 per 100,000), consistent with other Canadian estimates. As expected, impaired agility, vision, communication, mobility, pain, and memory were strongly associated with MS. Mental disorders were also associated with impairment, but interactions between these conditions and MS were generally not evident.
CONCLUSIONS: Mental disorders are associated with a higher level of disability in MS but, with the exception of communication, there was no evidence of synergistic interaction between mental disorders and MS in contributing to health-related impairments.

Entities:  

Mesh:

Year:  2012        PMID: 22641930     DOI: 10.2190/PM.43.1.d

Source DB:  PubMed          Journal:  Int J Psychiatry Med        ISSN: 0091-2174            Impact factor:   1.210


  4 in total

1.  Psychiatric comorbidity is associated with disability progression in multiple sclerosis.

Authors:  Kyla A McKay; Helen Tremlett; John D Fisk; Tingting Zhang; Scott B Patten; Lorne Kastrukoff; Trudy Campbell; Ruth Ann Marrie
Journal:  Neurology       Date:  2018-03-09       Impact factor: 9.910

Review 2.  The incidence and prevalence of psychiatric disorders in multiple sclerosis: a systematic review.

Authors:  Ruth Ann Marrie; Stephen Reingold; Jeffrey Cohen; Olaf Stuve; Maria Trojano; Per Soelberg Sorensen; Gary Cutter; Nadia Reider
Journal:  Mult Scler       Date:  2015-01-12       Impact factor: 6.312

3.  Recommendations for observational studies of comorbidity in multiple sclerosis.

Authors:  Ruth Ann Marrie; Aaron Miller; Maria Pia Sormani; Alan Thompson; Emmanuelle Waubant; Maria Trojano; Paul O'Connor; Kirsten Fiest; Nadia Reider; Stephen Reingold; Jeffrey A Cohen
Journal:  Neurology       Date:  2016-02-10       Impact factor: 9.910

4.  Psychiatric diagnoses, medication and risk for disability pension in multiple sclerosis patients; a population-based register study.

Authors:  Philip Brenner; Kristina Alexanderson; Charlotte Björkenstam; Jan Hillert; Jussi Jokinen; Ellenor Mittendorfer-Rutz; Petter Tinghög
Journal:  PLoS One       Date:  2014-08-05       Impact factor: 3.240

  4 in total

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