Literature DB >> 22635203

Traceless chemical ligations from O-acyl serine sites.

Mirna El Khatib1, Mohamed Elagawany, Farukh Jabeen, Ekaterina Todadze, Oleg Bol'shakov, Alexander Oliferenko, Levan Khelashvili, Said A el-Feky, Abdullah Asiri, Alan R Katritzky.   

Abstract

Chemical ligation via O- to N-acyl transfer of O-acylated serine containing peptides affords serine containing native peptides via 8- and 11-membered cyclic transition states opening the door to a wide variety of potential applications to peptide elaboration. The feasibility of these traceless chemical ligations is feasible as supported by computation.

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Year:  2012        PMID: 22635203     DOI: 10.1039/c2ob07050b

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

1.  Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH2 insertion.

Authors:  Mohamed Elagawany; Lingaiah Maram; Bahaa Elgendy
Journal:  RSC Adv       Date:  2021-02-17       Impact factor: 3.361

  1 in total

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