Literature DB >> 2263471

Synthesis and enzymatic polymerisation of 5-amino-1-(2'-deoxy-beta-D-ribofuranosyl)imidazole-4-carboxamide-5'- triphosphate.

S Pochet1, R D'Ari.   

Abstract

The chemical synthesis of 5-amino-1-(2'-deoxy-beta-D-ribofuranosyl)imidazole-4-carboxamide, referred to as dZ, and of its 5'-triphosphate derivative (dZTP), from 2'-deoxyinosine is described. The polymerisation of dZTP using terminal deoxynucleotidyltransferase to give a homopolymer is also presented.

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Year:  1990        PMID: 2263471      PMCID: PMC332778          DOI: 10.1093/nar/18.23.7127

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  10 in total

1.  Ribosidation of 4-amino-imidazole-5-carboxamide by Escherichia coli.

Authors:  R BEN-ISHAI; E D BERGMAN; B E VOLCANI
Journal:  Nature       Date:  1951-12-29       Impact factor: 49.962

2.  The enzymically catalysed transfer of the deoxyribosyl group from one purine or pyrimidine to another.

Authors:  W S MACNUTT
Journal:  Biochem J       Date:  1952-01       Impact factor: 3.857

3.  Factors affecting terminal deoxynucleotidyl transferase activity in cacodylate buffer.

Authors:  T P Chirpich
Journal:  Biochem Biophys Res Commun       Date:  1977-10-24       Impact factor: 3.575

4.  Synthesis of 2-deoxy-D-ribofuranosyl 5-amino- and 5-hydroxyaminoimidazole nucleosides by chemical methods and biotransformation.

Authors:  D Ewing; R W Humble; A Holy; G Mackenzie; G Shaw; I Votruba
Journal:  Nucleic Acids Symp Ser       Date:  1989

5.  Nucleosides of 2-azapurines and certain ring analogs.

Authors:  J A Montgomery; H J Thomas
Journal:  J Med Chem       Date:  1972-02       Impact factor: 7.446

Review 6.  Imidazole nucleosides and nucleotides.

Authors:  L B Townsend
Journal:  Chem Rev       Date:  1967-10       Impact factor: 60.622

7.  1-Glycosyl derivatives of 5-aminoimidazole-4-carboxamide.

Authors:  J A Montgomery; H J Thomas
Journal:  J Med Chem       Date:  1972-12       Impact factor: 7.446

8.  Terminal transferase: use of the tailing of DNA and for in vitro mutagenesis.

Authors:  G Deng; R Wu
Journal:  Methods Enzymol       Date:  1983       Impact factor: 1.600

9.  ZTP (5-amino 4-imidazole carboxamide riboside 5'-triphosphate): a proposed alarmone for 10-formyl-tetrahydrofolate deficiency.

Authors:  B R Bochner; B N Ames
Journal:  Cell       Date:  1982-07       Impact factor: 41.582

10.  Synthesis of carbocyclic purine nucleosides using key intermediates, carbocyclic AICA-ribosides.

Authors:  R Marumoto; Y Taniyama; T Fukuda
Journal:  Nucleic Acids Symp Ser       Date:  1987
  10 in total
  4 in total

1.  Purine biosynthetic intermediate-containing ribose-phosphate polymers as evolutionary precursors to RNA.

Authors:  Harold S Bernhardt; Roger K Sandwick
Journal:  J Mol Evol       Date:  2014-09-02       Impact factor: 2.395

2.  AICAR is not an endogenous mutagen in Escherichia coli.

Authors:  M Fox; N Frandsen; R D'Ari
Journal:  Mol Gen Genet       Date:  1993-09

3.  Excess histidine enzymes cause AICAR-independent filamentation in Escherichia coli.

Authors:  N Frandsen; R D'Ari
Journal:  Mol Gen Genet       Date:  1993-09

4.  Fluorescent probing for RNA molecules by an unnatural base-pair system.

Authors:  Michiko Kimoto; Tsuneo Mitsui; Yoko Harada; Akira Sato; Shigeyuki Yokoyama; Ichiro Hirao
Journal:  Nucleic Acids Res       Date:  2007-08-09       Impact factor: 16.971

  4 in total

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