Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Extracellular NAD(+): a danger signal hindering regulatory T cells.

Literature DB >> 22634347

Extracellular NAD(+): a danger signal hindering regulatory T cells.

Sahil Adriouch¹, Friedrich Haag, Olivier Boyer, Michel Seman, Friedrich Koch-Nolte.

Abstract

Endogenous danger signals released during cell damage contribute to alert the immune system. Typically, their release results in the activation and maturation of innate immune cells, and the production of pro-inflammatory cytokines. In addition, extracellular NAD(+) stimulates immune responses by hindering regulatory T cells (Tregs), and could, therefore, represent the prototype of a new category of danger signals.

Entities: Chemical

Mesh：

Substances：
NAD

Year: 2012 PMID： 22634347 DOI： 10.1016/j.micinf.2012.05.011

Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700

Keyword Cloud
Cited

22 in total

Review 1. NAD⁺ metabolism and its roles in cellular processes during ageing.

Authors: Anthony J Covarrubias; Rosalba Perrone; Alessia Grozio; Eric Verdin
Journal: Nat Rev Mol Cell Biol Date: 2020-12-22 Impact factor: 94.444

2. Perception of Damaged Self in Plants.

Authors: Qi Li; Chenggang Wang; Zhonglin Mou
Journal: Plant Physiol Date: 2020-01-06 Impact factor: 8.340

3. Changes in Neutrophil Metabolism upon Activation and Aging.

Authors: Barbara Christine Richer; Natallia Salei; Tamás Laskay; Karsten Seeger
Journal: Inflammation Date: 2018-03 Impact factor: 4.092

4. CD38 is expressed on inflammatory cells of the intestine and promotes intestinal inflammation.

Authors: Michael Schneider; Valéa Schumacher; Timo Lischke; Karsten Lücke; Catherine Meyer-Schwesinger; Joachim Velden; Friedrich Koch-Nolte; Hans-Willi Mittrücker
Journal: PLoS One Date: 2015-05-04 Impact factor: 3.240

5. A lectin receptor kinase as a potential sensor for extracellular nicotinamide adenine dinucleotide in Arabidopsis thaliana.

Authors: Chenggang Wang; Mingqi Zhou; Xudong Zhang; Jin Yao; Yanping Zhang; Zhonglin Mou
Journal: Elife Date: 2017-07-19 Impact factor: 8.140

Review 6. Aspects of Tryptophan and Nicotinamide Adenine Dinucleotide in Immunity: A New Twist in an Old Tale.

Authors: Hector Rodriguez Cetina Biefer; Anju Vasudevan; Abdallah Elkhal
Journal: Int J Tryptophan Res Date: 2017-06-14

7. Extracellular Degradation Into Adenosine and the Activities of Adenosine Kinase and AMPK Mediate Extracellular NAD⁺-Produced Increases in the Adenylate Pool of BV2 Microglia Under Basal Conditions.

Authors: Jie Zhang; Caixia Wang; Haibo Shi; Danhong Wu; Weihai Ying
Journal: Front Cell Neurosci Date: 2018-10-18 Impact factor: 5.505

Extracellular NAD(+): a danger signal hindering regulatory T cells.

Review 1. NAD⁺ metabolism and its roles in cellular processes during ageing.

2. Perception of Damaged Self in Plants.

3. Changes in Neutrophil Metabolism upon Activation and Aging.

4. CD38 is expressed on inflammatory cells of the intestine and promotes intestinal inflammation.

5. A lectin receptor kinase as a potential sensor for extracellular nicotinamide adenine dinucleotide in Arabidopsis thaliana.

Review 6. Aspects of Tryptophan and Nicotinamide Adenine Dinucleotide in Immunity: A New Twist in an Old Tale.

7. Extracellular Degradation Into Adenosine and the Activities of Adenosine Kinase and AMPK Mediate Extracellular NAD⁺-Produced Increases in the Adenylate Pool of BV2 Microglia Under Basal Conditions.

Review 8. Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function.

Review 9. NADomics: Measuring NAD⁺ and Related Metabolites Using Liquid Chromatography Mass Spectrometry.

10. Exogenous Nicotinamide Adenine Dinucleotide Induces Resistance to Citrus Canker in Citrus.

Extracellular NAD(+): a danger signal hindering regulatory T cells.

Review 1. NAD+ metabolism and its roles in cellular processes during ageing.

2. Perception of Damaged Self in Plants.

3. Changes in Neutrophil Metabolism upon Activation and Aging.

4. CD38 is expressed on inflammatory cells of the intestine and promotes intestinal inflammation.

5. A lectin receptor kinase as a potential sensor for extracellular nicotinamide adenine dinucleotide in Arabidopsis thaliana.

Review 6. Aspects of Tryptophan and Nicotinamide Adenine Dinucleotide in Immunity: A New Twist in an Old Tale.

7. Extracellular Degradation Into Adenosine and the Activities of Adenosine Kinase and AMPK Mediate Extracellular NAD+-Produced Increases in the Adenylate Pool of BV2 Microglia Under Basal Conditions.

Review 8. Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function.

Review 9. NADomics: Measuring NAD+ and Related Metabolites Using Liquid Chromatography Mass Spectrometry.

10. Exogenous Nicotinamide Adenine Dinucleotide Induces Resistance to Citrus Canker in Citrus.

Review 1. NAD⁺ metabolism and its roles in cellular processes during ageing.

7. Extracellular Degradation Into Adenosine and the Activities of Adenosine Kinase and AMPK Mediate Extracellular NAD⁺-Produced Increases in the Adenylate Pool of BV2 Microglia Under Basal Conditions.

Review 9. NADomics: Measuring NAD⁺ and Related Metabolites Using Liquid Chromatography Mass Spectrometry.