Literature DB >> 22633603

Alpinetin/hydroxypropyl-β-cyclodextrin host-guest system: preparation, characterization, inclusion mode, solubilization and stability.

Shui-Xian Ma1, Wen Chen, Xiao-Dong Yang, Na Zhang, Shao-Jie Wang, Lin Liu, Li-Juan Yang.   

Abstract

The inclusion complexation behavior, characterization and binding ability of alpinetin with hydroxypropyl-β-cyclodextrin (HPβCD) has been investigated in both solution and the solid state by means of UV-vis spectroscopy, FT-IR, ¹H and 2D NMR, XRD, SEM and DSC. The results showed that the water solubility and stability of alpinetin were obviously increased in the inclusion complex with HPβCD. This satisfactory water solubility and high stability of the alpinetin/HPβCD complex will be potentially useful for its application as herbal medicine or healthcare products.
Copyright © 2012 Elsevier B.V. All rights reserved.

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Year:  2012        PMID: 22633603     DOI: 10.1016/j.jpba.2012.04.038

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN: 0731-7085            Impact factor:   3.935


  9 in total

1.  β-Cyclodextrin-based inclusion complexes and nanocomposites of rivaroxaban for solubility enhancement.

Authors:  Atul P Sherje; Mrunal Jadhav
Journal:  J Mater Sci Mater Med       Date:  2018-12-06       Impact factor: 3.896

Review 2.  Alpinetin: a Dietary Flavonoid with Diverse Anticancer Effects.

Authors:  Sameena Gul; Muhammad Faisal Maqbool; Dongying Zheng; Yongming Li; Muhammad Khan; Tonghui Ma
Journal:  Appl Biochem Biotechnol       Date:  2022-05-14       Impact factor: 3.094

3.  A 5,7-dimethoxyflavone/hydroxypropyl-β-cyclodextrin inclusion complex with anti-butyrylcholinesterase activity.

Authors:  Supachai Songngam; Mongkol Sukwattanasinitt; Krisana Siralertmukul; Pattara Sawasdee
Journal:  AAPS PharmSciTech       Date:  2014-05-31       Impact factor: 3.246

4.  Methyl-β-cyclodextrin Inclusion Complex with β-Caryophyllene: Preparation, Characterization, and Improvement of Pharmacological Activities.

Authors:  Pauline S Santos; Luan K M Souza; Thiago S L Araújo; Jand Venes R Medeiros; Sandra C C Nunes; Rui A Carvalho; Alberto C C Pais; Francisco J B Veiga; Lívio C C Nunes; Ana Figueiras
Journal:  ACS Omega       Date:  2017-12-18

5.  Synthesis and Characterization of Phenolic Acid/Hydroxypropyl-β-Cyclodextrin Inclusion Complexes.

Authors:  Ji-Sang Kim
Journal:  Prev Nutr Food Sci       Date:  2020-12-31

Review 6.  Alpinetin: A Review of Its Pharmacology and Pharmacokinetics.

Authors:  Ge Zhao; Yue Tong; Fei Luan; Wenjing Zhu; Chenglin Zhan; Tiantian Qin; Weixiao An; Nan Zeng
Journal:  Front Pharmacol       Date:  2022-02-04       Impact factor: 5.810

7.  Therapeutic efficacy of an injectable formulation of purinostat mesylate in SU-DHL-6 tumour model.

Authors:  Zejiang Zhu; Jiaolin Wen; Yaohui Xu; Heying Pei; Dan Li; Minghai Tang; Peng Bai; Jun He; Zhuang Yang; Lijuan Chen
Journal:  Ann Med       Date:  2022-12       Impact factor: 4.709

8.  Changes in the Physicochemical Properties of Piperine/β-Cyclodextrin due to the Formation of Inclusion Complexes.

Authors:  Toshinari Ezawa; Yutaka Inoue; Sujimon Tunvichien; Rina Suzuki; Ikuo Kanamoto
Journal:  Int J Med Chem       Date:  2016-02-22

9.  Hydrophobically Modified Glucan as an Amphiphilic Carbohydrate Polymer for Micellar Delivery of Myricetin.

Authors:  Weiyu Yang; Ling Guo; Fenfen Li; Xin Liu; Shaoping Nie; Mingyong Xie; Danfei Huang
Journal:  Molecules       Date:  2019-10-17       Impact factor: 4.411

  9 in total

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