| Literature DB >> 22632656 |
Olaf Hartmann1, Markus Kalesse.
Abstract
The first total synthesis of (-)-aurafuron A is presented. It features a Suzuki cross-coupling reaction and a high yielding anionic aldol addition as central carbon skeleton building reactions. The synthesis confirms the proposed structure including its configuration and allows for detailed SAR studies.Entities:
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Year: 2012 PMID： 22632656 DOI： 10.1021/ol3011387
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005