BACKGROUND: This pilot study evaluated an intervention designed to enhance adherence among those new to antiretroviral therapy. METHODS:Participants (n = 80) were recruited from a hospital clinic in Chandigarh, India, and randomized to a 3-month group intervention or individual enhanced standard of care followed by crossover of condition and assessed over 6 months. Adherence was measured by prescription refill, pill count, and self-report. RESULTS: At baseline, 56% of group condition (immediate intervention) and 54% of individual condition (delayed intervention) participants were nonadherent by pill count and 23% of group and 26% of individual condition participants self-reported skipping medication at least once over the last 3 months. From the postintervention to long-term follow-up, adherence in the group condition (immediate intervention) improved in comparison with adherence in the individual condition (delayed intervention; χ(2) = 5.67, P = .02). CONCLUSIONS: Results support the use of interventions early in treatment to provide information and social support to establish long-term healthy adherence behaviors.
RCT Entities:
BACKGROUND: This pilot study evaluated an intervention designed to enhance adherence among those new to antiretroviral therapy. METHODS:Participants (n = 80) were recruited from a hospital clinic in Chandigarh, India, and randomized to a 3-month group intervention or individual enhanced standard of care followed by crossover of condition and assessed over 6 months. Adherence was measured by prescription refill, pill count, and self-report. RESULTS: At baseline, 56% of group condition (immediate intervention) and 54% of individual condition (delayed intervention) participants were nonadherent by pill count and 23% of group and 26% of individual condition participants self-reported skipping medication at least once over the last 3 months. From the postintervention to long-term follow-up, adherence in the group condition (immediate intervention) improved in comparison with adherence in the individual condition (delayed intervention; χ(2) = 5.67, P = .02). CONCLUSIONS: Results support the use of interventions early in treatment to provide information and social support to establish long-term healthy adherence behaviors.
Authors: Kartik K Venkatesh; A K Srikrishnan; Kenneth H Mayer; N Kumarasamy; Sudha Raminani; E Thamburaj; Lakshmi Prasad; Elizabeth W Triche; Suniti Solomon; Steven A Safren Journal: AIDS Patient Care STDS Date: 2010-11-22 Impact factor: 5.078
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Authors: Lina Margarita Bofill; Maria Lopez; Analia Dorigo; Alejandra Bordato; Mar Lucas; Graciela Fernandez Cabanillas; Omar Sued; Pedro Cahn; Isabel Cassetti; Stephen Weiss; Deborah Jones Journal: AIDS Care Date: 2013-10-21
Authors: Kathleen Ridgeway; Lisa S Dulli; Kate R Murray; Hannah Silverstein; Leila Dal Santo; Patrick Olsen; Danielle Darrow de Mora; Donna R McCarraher Journal: PLoS One Date: 2018-01-02 Impact factor: 3.240