Literature DB >> 22627803

Improved arterial visualization in cerebral CT perfusion-derived arteriograms compared with standard CT angiography: a visual assessment study.

A M Mendrik1, E P A Vonken, G A P de Kort, B van Ginneken, E J Smit, M A Viergever, M Prokop.   

Abstract

BACKGROUND AND
PURPOSE: Invasive cerebral DSA has largely been replaced by CTA, which is noninvasive but has a compromised arterial view due to superimposed bone and veins. The purpose of this study was to evaluate whether arterial visualization in CTPa is superior to standard CTA, which would eliminate the need for an additional CTA scan to assess arterial diseases and therefore reduce radiation dose.
MATERIALS AND METHODS: In this study, we included 24 patients with subarachnoid hemorrhage for whom CTA and CTP were available. Arterial quality and presence of superimposed veins and bone in CTPa were compared with CTA and scored by 2 radiologists by using a VAS (0%-100%). Average VAS scores were determined and VAS scores per patient were converted to a 10-point NRS. Arterial visualization was considered to be improved when the highest rate (NRS 10, VAS > 90%) was scored for arterial quality, and the lowest rate (NRS 1, VAS < 10%), for the presence of superimposed veins and bone. A sign test with continuity correction was used to test whether the number of cases with these rates was significant.
RESULTS: Average VAS scores in the proximal area were 94% (arterial quality), 4% (presence of bone), and 7% (presence of veins). In this area, the sign test showed that a significant number of cases scored NRS 10 for arterial quality (P < .02) and NRS 1 for the presence of superimposed veins and bone (P < .01).
CONCLUSIONS: Cerebral CTPa shows improved arterial visualization in the proximal area compared with CTA, with similar arterial quality but no superimposed bone and veins.

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Year:  2012        PMID: 22627803      PMCID: PMC7965587          DOI: 10.3174/ajnr.A3118

Source DB:  PubMed          Journal:  AJNR Am J Neuroradiol        ISSN: 0195-6108            Impact factor:   3.825


  20 in total

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2.  Automatic segmentation of intracranial arteries and veins in four-dimensional cerebral CT perfusion scans.

Authors:  Adriënne Mendrik; Evert-Jan Vonken; Bram van Ginneken; Ewoud Smit; Annet Waaije; Giovanna Bertolini; Max A Viergever; Mathias Prokop
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2.  Endothelin-1 expression and alterations of cerebral microcirculation after experimental subarachnoid hemorrhage.

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3.  Total bolus extraction method improves arterial image quality in dynamic CTAs derived from whole-brain CTP data.

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