| Literature DB >> 22626446 |
Gavin Carr1, David E Williams, Rukmal Ratnayake, Ratnayake Bandara, Siril Wijesundara, Tamsin Tarling, Aruna D Balgi, Michel Roberge, Raymond J Andersen, Veranja Karunaratne.
Abstract
The new hexahydroazulenones hortonones A (1) to C (3) were isolated from the leaves of three representative species of the endemic Sri Lankan genus Hortonia that belongs to the family Monimiaceae. Hortonones A (1) and B (2) have the unprecedented rearranged hortonane sesquiterpenoid carbon skeleton, and hortonone C (3) has the unprecedented rearranged and degraded 13-norhortonane skeleton. Hortonone C (3) exhibited in vitro cytotoxicity against human breast cancer MCF-7 cells at 5 μg/mL.Entities:
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Year: 2012 PMID： 22626446 DOI： 10.1021/np200927k
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050