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Literature DB >> 22623784

Switching on RNA silencing suppressor activity by restoring argonaute binding to a viral protein.

Edit Z Szabó¹, Máté Manczinger, Anikó Göblös, Lajos Kemény, Lóránt Lakatos.

Abstract

We found that Sweet potato feathery mottle virus (SPFMV) P1, a close homologue of Sweet potato mild mottle virus P1, did not have any silencing suppressor activity. Remodeling the Argonaute (AGO) binding domain of SPFMV P1 by the introduction of two additional WG/GW motifs converted it to a silencing suppressor with AGO binding capacity. To our knowledge, this is the first instance of the transformation of a viral protein of unknown function to a functional silencing suppressor.

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Year: 2012 PMID： 22623784 PMCID： PMC3421681 DOI： 10.1128/JVI.00627-12

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

16 in total

1. RNA polymerase IV directs silencing of endogenous DNA.

Authors: A J Herr; M B Jensen; T Dalmay; D C Baulcombe
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2. An RNA-dependent RNA polymerase prevents meristem invasion by potato virus X and is required for the activity but not the production of a systemic silencing signal.

Authors: Frank Schwach; Fabian E Vaistij; Louise Jones; David C Baulcombe
Journal: Plant Physiol Date: 2005-07-22 Impact factor: 8.340

3. Small RNA binding is a common strategy to suppress RNA silencing by several viral suppressors.

Authors: Lóránt Lakatos; Tibor Csorba; Vitantonio Pantaleo; Elisabeth J Chapman; James C Carrington; Yu-Ping Liu; Valerian V Dolja; Lourdes Fernández Calvino; Juan José López-Moya; József Burgyán
Journal: EMBO J Date: 2006-05-25 Impact factor: 11.598

4. Recombination and gene duplication in the evolutionary diversification of P1 proteins in the family Potyviridae.

Authors: Adrian Valli; Juan José López-Moya; Juan Antonio García
Journal: J Gen Virol Date: 2007-03 Impact factor: 3.891

5. A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain.

Authors: Susanne Till; Erwan Lejeune; Rolf Thermann; Miriam Bortfeld; Michael Hothorn; Daniel Enderle; Constanze Heinrich; Matthias W Hentze; Andreas G Ladurner
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Review 6. Intercellular and systemic movement of RNA silencing signals.

Authors: Charles W Melnyk; Attila Molnar; David C Baulcombe
Journal: EMBO J Date: 2011-08-31 Impact factor: 11.598

7. SDE3 encodes an RNA helicase required for post-transcriptional gene silencing in Arabidopsis.

Authors: T Dalmay; R Horsefield; T H Braunstein; D C Baulcombe
Journal: EMBO J Date: 2001-04-17 Impact factor: 11.598

8. Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense.

Authors: Xiuren Zhang; Yu-Ren Yuan; Yi Pei; Shih-Shun Lin; Thomas Tuschl; Dinshaw J Patel; Nam-Hai Chua
Journal: Genes Dev Date: 2006-12-01 Impact factor: 11.361

9. Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components.

Authors: Mahmoud El-Shami; Dominique Pontier; Sylvie Lahmy; Laurence Braun; Claire Picart; Danielle Vega; Mohamed-Ali Hakimi; Steven E Jacobsen; Richard Cooke; Thierry Lagrange
Journal: Genes Dev Date: 2007-10-15 Impact factor: 11.361

10. Both introns and long 3'-UTRs operate as cis-acting elements to trigger nonsense-mediated decay in plants.

Authors: Sándor Kertész; Zoltán Kerényi; Zsuzsanna Mérai; Imre Bartos; Tamás Pálfy; Endre Barta; Dániel Silhavy
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8 in total

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Authors: Alberto Carbonell; James C Carrington
Journal: Curr Opin Plant Biol Date: 2015-07-17 Impact factor: 7.834

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Authors: Ares Mingot; Adrián Valli; Bernardo Rodamilans; David San León; David C Baulcombe; Juan Antonio García; Juan José López-Moya
Journal: J Virol Date: 2016-01-20 Impact factor: 5.103

3. P1 of Sweet Potato Feathery Mottle Virus Shows Strong Adaptation Capacity, Replacing P1-HCPro in a Chimeric Plum Pox Virus.

Authors: B Rodamilans; A Casillas; J A García
Journal: J Virol Date: 2021-06-24 Impact factor: 5.103

Review 4. Suppress to Survive-Implication of Plant Viruses in PTGS.

Authors: Przemysław Wieczorek; Aleksandra Obrępalska-Stęplowska
Journal: Plant Mol Biol Report Date: 2015 Impact factor: 1.595

5. A novel sweet potato potyvirus open reading frame (ORF) is expressed via polymerase slippage and suppresses RNA silencing.

Authors: Milton Untiveros; Allan Olspert; Katrin Artola; Andrew E Firth; Jan F Kreuze; Jari P T Valkonen
Journal: Mol Plant Pathol Date: 2016-04-28 Impact factor: 5.663

6. Translational control in plant antiviral immunity.

Authors: João Paulo B Machado; Iara P Calil; Anésia A Santos; Elizabeth P B Fontes
Journal: Genet Mol Biol Date: 2017-02-13 Impact factor: 1.771

7. An atypical RNA silencing suppression strategy provides a snapshot of the evolution of sweet potato-infecting potyviruses.

Authors: Bernardo Rodamilans; Adrián Valli; Ares Mingot; David San León; Juan José López-Moya; Juan Antonio García
Journal: Sci Rep Date: 2018-10-29 Impact factor: 4.379

8. s8ORF2 protein of infectious salmon anaemia virus is a RNA-silencing suppressor and interacts with Salmon salar Mov10 (SsMov10) of the host RNAi machinery.

Authors: Vandana Thukral; Bhavna Varshney; Rimatulhana B Ramly; Sanket S Ponia; Sumona Karjee Mishra; Christel M Olsen; Akhil C Banerjea; Sunil K Mukherjee; Rana Zaidi; Espen Rimstad; Sunil K Lal
Journal: Virus Genes Date: 2017-12-07 Impact factor: 2.332

8 in total