Literature DB >> 22622552

Antibiotics: Recover the lost art of drug discovery.

Kim Lewis1.   

Abstract

Mesh:

Substances:

Year:  2012        PMID: 22622552     DOI: 10.1038/485439a

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


× No keyword cloud information.
  4 in total

Review 1.  Persister cells.

Authors:  Kim Lewis
Journal:  Annu Rev Microbiol       Date:  2010       Impact factor: 15.500

Review 2.  Uncultured microorganisms as a source of secondary metabolites.

Authors:  Kim Lewis; Slava Epstein; Anthony D'Onofrio; Losee L Ling
Journal:  J Antibiot (Tokyo)       Date:  2010-07-21       Impact factor: 2.649

Review 3.  Molecular mechanisms of antibacterial multidrug resistance.

Authors:  Michael N Alekshun; Stuart B Levy
Journal:  Cell       Date:  2007-03-23       Impact factor: 41.582

Review 4.  Tackling antibiotic resistance.

Authors:  Karen Bush; Patrice Courvalin; Gautam Dantas; Julian Davies; Barry Eisenstein; Pentti Huovinen; George A Jacoby; Roy Kishony; Barry N Kreiswirth; Elizabeth Kutter; Stephen A Lerner; Stuart Levy; Kim Lewis; Olga Lomovskaya; Jeffrey H Miller; Shahriar Mobashery; Laura J V Piddock; Steven Projan; Christopher M Thomas; Alexander Tomasz; Paul M Tulkens; Timothy R Walsh; James D Watson; Jan Witkowski; Wolfgang Witte; Gerry Wright; Pamela Yeh; Helen I Zgurskaya
Journal:  Nat Rev Microbiol       Date:  2011-11-02       Impact factor: 60.633

  4 in total
  60 in total

1.  Drug discovery: spread the risk of antibiotic research.

Authors:  Chris Schofield
Journal:  Nature       Date:  2012-06-20       Impact factor: 49.962

Review 2.  Antibacterial drug discovery in the resistance era.

Authors:  Eric D Brown; Gerard D Wright
Journal:  Nature       Date:  2016-01-21       Impact factor: 49.962

3.  Lassomycin, a ribosomally synthesized cyclic peptide, kills mycobacterium tuberculosis by targeting the ATP-dependent protease ClpC1P1P2.

Authors:  Ekaterina Gavrish; Clarissa S Sit; Shugeng Cao; Olga Kandror; Amy Spoering; Aaron Peoples; Losee Ling; Ashley Fetterman; Dallas Hughes; Anthony Bissell; Heather Torrey; Tatos Akopian; Andreas Mueller; Slava Epstein; Alfred Goldberg; Jon Clardy; Kim Lewis
Journal:  Chem Biol       Date:  2014-03-27

4.  A screen for and validation of prodrug antimicrobials.

Authors:  Laura E Fleck; E Jeffrey North; Richard E Lee; Lawrence R Mulcahy; Gabriele Casadei; Kim Lewis
Journal:  Antimicrob Agents Chemother       Date:  2013-12-16       Impact factor: 5.191

Review 5.  The gut microbiota-a clinical perspective on lessons learned.

Authors:  Fergus Shanahan
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2012-08-14       Impact factor: 46.802

6.  Drug discovery: Early antibiotic from a cranberry bog.

Authors:  Carol L Moberg
Journal:  Nature       Date:  2015-02-19       Impact factor: 49.962

Review 7.  Leveraging synthetic biology for producing bioactive polyketides and non-ribosomal peptides in bacterial heterologous hosts.

Authors:  Taylor B Cook; Brian F Pfleger
Journal:  Medchemcomm       Date:  2019-04-25       Impact factor: 3.597

8.  Molecular Properties That Define the Activities of Antibiotics in Escherichia coli and Pseudomonas aeruginosa.

Authors:  Connor J Cooper; Ganesh Krishnamoorthy; David Wolloscheck; John K Walker; Valentin V Rybenkov; Jerry M Parks; Helen I Zgurskaya
Journal:  ACS Infect Dis       Date:  2018-05-25       Impact factor: 5.084

9.  Design, synthesis, and biological evaluation of α-hydroxyacyl-AMS inhibitors of amino acid adenylation enzymes.

Authors:  Tony D Davis; Poornima Mohandas; Maria I Chiriac; Glennon V Bythrow; Luis E N Quadri; Derek S Tan
Journal:  Bioorg Med Chem Lett       Date:  2016-09-16       Impact factor: 2.823

Review 10.  Pseudomonas aeruginosa biofilms in disease.

Authors:  Lawrence R Mulcahy; Vincent M Isabella; Kim Lewis
Journal:  Microb Ecol       Date:  2013-10-06       Impact factor: 4.552

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.