| Literature DB >> 2262243 |
R Zanetti1, S Franceschi, S Rosso, E Bidoli, S Colonna.
Abstract
The role of hormonal and reproductive factors as risks for cutaneous malignant melanoma (CMM) was explored by means of a population-based case-control study conducted in Turin, north-western Italy, on 186 female CMM cases and 205 controls. Past use of oral contraceptives (OC) did not seem to exert any effect on CMM risk odds ratio (OR) = 1.12, 95% confidence interval (CI): 0.56-2.24). No association was found even for the longest duration of use, for superficial spreading melanoma cases and for CMM of lower limbs only. While age at first birth did not affect CMM risk, women who had had three or more children seemed to be significantly protected as compared to nulliparous ones. The association was, however, substantially diminished by adjustment for education and other CMM risk correlates (OR for at least three children versus none = 0.62; 95% Cl: 0.29-1.31).Entities:
Keywords: Age Distribution; Age Factors; Biology; Cancer--etiology; Case Control Studies; Case Studies; Contraception; Contraceptive Methods; Data Analysis; Data Collection; Demographic Factors; Dermatological Effects; Developed Countries; Diseases; Europe; Family Planning; Fertility; Fertility Measurements; Histology; Italy; Mediterranean Countries; Neoplasms; Oral Contraceptives; Parity; Physiology; Population; Population Characteristics; Population Dynamics; Research Methodology; Risk Factors; Southern Europe; Studies; Time Factors
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Year: 1990 PMID： 2262243 DOI： 10.1093/ije/19.3.522
Source DB: PubMed Journal: Int J Epidemiol ISSN： 0300-5771 Impact factor: 7.196