Literature DB >> 22619138

Testicular cancer: our experience after 10 years.

Maria Esther Valsero Herguedas1, Miguel Pascual Samaniego, Elena Garcia Lagarto, Sergio Martín Martin, Maria Fe Muñoz Moreno, Jose Ramon Cortiñas Gonzalez.   

Abstract

OBJECTIVES: Testicular cancer represents about 1% of malignant tumors in men. Of these tumors 95% are germ cell tumors (GCTs), which have a maximum incidence between the second and third decades of life. Our objective was to carry out a retrospective analysis of testicular tumor cases that had been diagnosed in our Health Area between the years 2000 and 2010.
METHODS: We performed a retrospective descriptive study between the years 2000 and 2010 analyzing 43 patients treated for testicular cancer, including in the analysis tumor incidence, the patient's age, clinic attended, patient's time until appointment, presence of tumor markers, patient's time before treatment, use of testicular prostheses, histological type and their typical characteristics, oncological treatment, tumor progression and mortality rate.
RESULTS: We found an incidence of 4-5 cases/100,000 population/year in our Health Area. Two-thirds of the cases were detected in Stage I, and 100% of these cases showed complete remission. Among those with higher stage tumors, two out of three patients were cured after chemotherapy. For the remaining one-third, rescue treatments managed to achieve a remission rate of 66%. Mortality was low and was linked to lymphoma or metastatic dissemination.
CONCLUSION: The trend towards early diagnosis with detection during the initial cancer stages, together with current chemotherapy protocols, enables a high cure rate for testicular cancer. Mortality in our series was associated with primary or secondary lymphomas.

Entities:  

Mesh:

Substances:

Year:  2012        PMID: 22619138

Source DB:  PubMed          Journal:  Arch Esp Urol        ISSN: 0004-0614            Impact factor:   0.436


  2 in total

1.  Antioxidant enzyme profile and lipid peroxidation products in semen samples of testicular germ cell tumor patients submitted to orchiectomy.

Authors:  Camila Sposito; Mariana Camargo; Danielle Spinola Tibaldi; Valéria Barradas; Agnaldo Pereira Cedenho; Marcílio Nichi; Ricardo Pimenta Bertolla; Deborah Montagnini Spaine
Journal:  Int Braz J Urol       Date:  2017 Jul-Aug       Impact factor: 1.541

2.  Malignant testicular tumour incidence and mortality trends.

Authors:  Barbara Stawińska-Witoszyńska; Paulina Wojtyła-Buciora; Barbara Więckowska; Małgorzata Krzywinska-Wiewiorowska; Małgorzata Gromadecka-Sutkiewicz
Journal:  Contemp Oncol (Pozn)       Date:  2016-03-16
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.