PURPOSE: To investigate the association between preoperative low serum albumin level and acute kidney injury (AKI) after off-pump coronary artery bypass surgery (OPCAB) METHOD: We assessed preoperative and perioperative risk factors, and preoperative serum albumin concentration in 1,182 consecutive adult patients with preoperative normal renal function who underwent OPCAB surgery. Each patient was categorized by maximal Acute Kidney Injury Network (AKIN) criteria based on creatinine changes within the first 48 h after OPCAB. Logistic regression and propensity analyses were performed to evaluate the association between preoperative low serum albumin level and postoperative AKI. RESULTS: Of the 1,182 patients, 334 (28.3%) developed AKI. Risk factors for AKI were old age, diabetes mellitus, maximal cardiovascular component of the sequential organ failure assessment score, perioperative transfusion, and postoperative C-reactive protein concentration. The risk of AKI was negatively correlated with the volume of crystalloid infused during surgery. A preoperative serum albumin level of <4.0 g/dl was independently associated Ith postoperative AKI [multivariable logistic analysis: odds ratio (OR) 1.83, 95 % confidence interval (CI) 1.27-2.64; P = 0.001; propensity analysis: OR 1.62, 95 % CI 1.12-2.35; P = 0.011). AKI was associated with prolonged stay in the intensive care unit and hospital and a high mortality rate. CONCLUSIONS: Preoperative low serum albumin level is an independent risk factor for AKI, and postoperative AKI is associated with poor outcomes after OPCAB in patients with preoperative normal renal function.
PURPOSE: To investigate the association between preoperative low serum albumin level and acute kidney injury (AKI) after off-pump coronary artery bypass surgery (OPCAB) METHOD: We assessed preoperative and perioperative risk factors, and preoperative serum albumin concentration in 1,182 consecutive adult patients with preoperative normal renal function who underwent OPCAB surgery. Each patient was categorized by maximal Acute Kidney Injury Network (AKIN) criteria based on creatinine changes within the first 48 h after OPCAB. Logistic regression and propensity analyses were performed to evaluate the association between preoperative low serum albumin level and postoperative AKI. RESULTS: Of the 1,182 patients, 334 (28.3%) developed AKI. Risk factors for AKI were old age, diabetes mellitus, maximal cardiovascular component of the sequential organ failure assessment score, perioperative transfusion, and postoperative C-reactive protein concentration. The risk of AKI was negatively correlated with the volume of crystalloid infused during surgery. A preoperative serum albumin level of <4.0 g/dl was independently associated Ith postoperative AKI [multivariable logistic analysis: odds ratio (OR) 1.83, 95 % confidence interval (CI) 1.27-2.64; P = 0.001; propensity analysis: OR 1.62, 95 % CI 1.12-2.35; P = 0.011). AKI was associated with prolonged stay in the intensive care unit and hospital and a high mortality rate. CONCLUSIONS: Preoperative low serum albumin level is an independent risk factor for AKI, and postoperative AKI is associated with poor outcomes after OPCAB in patients with preoperative normal renal function.
Authors: Janet M Boyle; Soundous Moualla; Susana Arrigain; Sarah Worley; Mohamed H Bakri; Randall C Starling; Robert Heyka; Charuhas V Thakar Journal: Am J Kidney Dis Date: 2006-11 Impact factor: 8.860
Authors: Kim I de la Cruz; Faisal G Bakaeen; Xing Li Wang; Joseph Huh; Scott A LeMaire; Joseph S Coselli; Danny Chu Journal: Ann Thorac Surg Date: 2011-03 Impact factor: 4.330
Authors: Amit Lahoti; Hagop Kantarjian; Abdulla K Salahudeen; Farhad Ravandi; Jorge E Cortes; Stefan Faderl; Susan O'Brien; William Wierda; Gloria N Mattiuzzi Journal: Cancer Date: 2010-09-01 Impact factor: 6.860
Authors: John Kevin Hix; Charuhas V Thakar; Ethan M Katz; Jean-Pierre Yared; Joseph Sabik; Emil P Paganini Journal: Crit Care Med Date: 2006-12 Impact factor: 7.598
Authors: B A Pockaj; J C Yang; M T Lotze; J R Lange; W F Spencer; S M Steinberg; S L Topalian; D J Schwartzentruber; D E White; S A Rosenberg Journal: J Immunother Emphasis Tumor Immunol Date: 1994-01
Authors: Ravindra L Mehta; John A Kellum; Sudhir V Shah; Bruce A Molitoris; Claudio Ronco; David G Warnock; Adeera Levin Journal: Crit Care Date: 2007 Impact factor: 9.097
Authors: Shveta S Motwani; Gearoid M McMahon; Benjamin D Humphreys; Ann H Partridge; Sushrut S Waikar; Gary C Curhan Journal: J Clin Oncol Date: 2018-01-10 Impact factor: 44.544
Authors: Arwa Nada; David Askenazi; Juan C Kupferman; Maroun Mhanna; John D Mahan; Louis Boohaker; Linzi Li; Russell L Griffin Journal: Pediatr Nephrol Date: 2021-10-18 Impact factor: 3.651
Authors: Yen-Yi Juo; Matthew Skancke; Jeremy Holzmacher; Richard L Amdur; Paul P Lin; Khashayar Vaziri Journal: Surg Endosc Date: 2016-06-22 Impact factor: 4.584