Literature DB >> 22613778

GHEP-ISFG proficiency test 2011: Paper challenge on evaluation of mitochondrial DNA results.

L Prieto1, C Alves, B Zimmermann, A Tagliabracci, V Prieto, M Montesino, M R Whittle, M J Anjos, S Cardoso, B Heinrichs, A Hernandez, A M López-Parra, A Sala, V G Saragoni, G Burgos, M Marino, M Paredes, C A Mora-Torres, R Angulo, G Chemale, C Vullo, M Sánchez-Simón, D Comas, J Puente, C M López-Cubría, N Modesti, M Aler, S Merigioli, E Betancor, S Pedrosa, G Plaza, M V Masciovecchio, P M Schneider, W Parson.   

Abstract

The GHEP-ISFG Working Group performed a collaborative exercise to monitor the current practice of mitochondrial (mt)DNA reporting. The participating laboratories were invited to evaluate a hypothetical case example and assess the statistical significance of a match between the haplotypes of a case (hair) sample and a suspect. A total of 31 forensic laboratories participated of which all but one used the EMPOP database. Nevertheless, we observed a tenfold range of reported LR values (32-333.4), which was mainly due to the selection of different reference datasets in EMPOP but also due to different applied formulae. The results suggest the need for more standardization as well as additional research to harmonize the reporting of mtDNA evidence.
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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Year:  2012        PMID: 22613778     DOI: 10.1016/j.fsigen.2012.04.006

Source DB:  PubMed          Journal:  Forensic Sci Int Genet        ISSN: 1872-4973            Impact factor:   4.882


  1 in total

1.  Mitochondrial DNA control region diversity in a population from Espirito Santo state, Brazil.

Authors:  Naiara M Sanches; Greiciane G Paneto; Raquel F Figueiredo; Aline O de Mello; Regina M B Cicarelli
Journal:  Mol Biol Rep       Date:  2014-07-05       Impact factor: 2.316

  1 in total

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