Literature DB >> 22611953

Sentinel node disection in the treatment of early stages of vulvar cancer.

A García-Iglesias1, M O Rodríguez-Martín, R Ruano, D Beltrán, L Peñalosa, B Hernández-Barreiro, A Martín de Arriba, J L Lanchares.   

Abstract

OBJECTIVES: To assess the results of sentinel lymph node (SLN) detection in the initial stages of vulvar cancer and the recurrences that may appear. STUDY
DESIGN: 76 patients with vulvar carcinoma, Stage I and II. Between 2000 and 2010, identification of the SLN was performed with a perilesional injection of Tc99m and vital dye. Ninety sentinel lymph nodes were found. They were removed separately, and lymphadenectomy was performed depending on the involved areas. Vulvar tumour was also removed.
RESULTS: 76 patients were included in the study; 20 (22.22%) out of 90 SLNs presented metastases and 70 (77.77%) did not. There were no false negatives, and the sensitivity and negative predictive value reached 100%. Thirty-six months after treatment, one patient presented recurrence with a negative SLN, and two with positive SLNs.
CONCLUSION: Biopsy of the SLN is a reasonable alternative to lymphadenectomy in patients with vulvar cancer Stage I and II.

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Year:  2012        PMID: 22611953

Source DB:  PubMed          Journal:  Eur J Gynaecol Oncol        ISSN: 0392-2936            Impact factor:   0.196


  2 in total

Review 1.  Detection of sentinel lymph node in vulvar cancer using 99mTc-labeled colloid lymphoscintigraphy, blue dye, and indocyanine-green fluorescence: a meta-analysis of studies published in 2010-2020.

Authors:  Mariano Catello Di Donna; Natale Quartuccio; Vincenzo Giallombardo; Letterio Sturiale; Annachiara Arnone; Rosaria Ricapito; Giulio Sozzi; Gaspare Arnone; Vito Chiantera
Journal:  Arch Gynecol Obstet       Date:  2022-05-24       Impact factor: 2.344

Review 2.  Lymphoscintigraphy and sentinel lymph node biopsy in vulvar carcinoma: update from a European expert panel.

Authors:  Angela Collarino; Valentina Fuoco; Giorgia Garganese; Lenka M Pereira Arias-Bouda; Germano Perotti; Gianpiero Manca; Sergi Vidal-Sicart; Francesco Giammarile; Lioe-Fee de Geus-Oei; Giovanni Scambia; Alessandro Giordano; Renato A Valdés-Olmos; Marco Maccauro
Journal:  Eur J Nucl Med Mol Imaging       Date:  2020-01-02       Impact factor: 9.236

  2 in total

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