Literature DB >> 22610659

Nanoporous peptide particles for encapsulating and releasing neurotrophic factors in an animal model of neurodegeneration.

Justin Tan1, Yajun Wang, Xiaopei Yip, Fergal Glynn, Robert K Shepherd, Frank Caruso.   

Abstract

Neurotrophin-BDNF can be effectively encapsulated in nanoporous poly(L-glutamic acid) particles prepared via mesoporous silica templating. The loaded BDNF can be released in a sustained manner with retained biological activity. Animal experiments demonstrate the released BDNF can efficiently rescue the auditory neurons (as indicated by the arrows) in the cochlea of guinea pigs with sensorineural hearing loss.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22610659      PMCID： PMC3543853          DOI： 10.1002/adma.201200634

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  29 in total

1.  Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells.

Authors:  M Encinas; M Iglesias; Y Liu; H Wang; A Muhaisen; V Ceña; C Gallego; J X Comella
Journal:  J Neurochem       Date:  2000-09       Impact factor: 5.372

Review 2.  Auditory system development: primary auditory neurons and their targets.

Authors:  Edwin W Rubel; Bernd Fritzsch
Journal:  Annu Rev Neurosci       Date:  2002-02-05       Impact factor: 12.449

3.  Neurotrophins are key mediators of the myelination program in the peripheral nervous system.

Authors:  J R Chan; J M Cosgaya; Y J Wu; E M Shooter
Journal:  Proc Natl Acad Sci U S A       Date:  2001-11-20       Impact factor: 11.205

Review 4.  Aminoglycoside antibiotics.

Authors:  A Forge; J Schacht
Journal:  Audiol Neurootol       Date:  2000 Jan-Feb       Impact factor: 1.854

5.  Essential role for TrkB receptors in hippocampus-mediated learning.

Authors:  L Minichiello; M Korte; D Wolfer; R Kühn; K Unsicker; V Cestari; C Rossi-Arnaud; H P Lipp; T Bonhoeffer; R Klein
Journal:  Neuron       Date:  1999-10       Impact factor: 17.173

6.  A novel microperfusion system for the long-term local supply of drugs to the inner ear: implantation and function in the rat model.

Authors:  M Praetorius; A Limberger; M Müller; R Lehner; B Schick; H P Zenner; P Plinkert; M Knipper
Journal:  Audiol Neurootol       Date:  2001 Sep-Oct       Impact factor: 1.854

Review 7.  Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease.

Authors:  M G Murer; Q Yan; R Raisman-Vozari
Journal:  Prog Neurobiol       Date:  2001-01       Impact factor: 11.685

8.  Viability, adhesion, and bone phenotype of osteoblast-like cells on polyelectrolyte multilayer films.

Authors:  Petra Tryoen-Tóth; Dominique Vautier; Youssef Haikel; Jean-Claude Voegel; Pierre Schaaf; Johanna Chluba; Joëlle Ogier
Journal:  J Biomed Mater Res       Date:  2002-06-15

9.  Polysaccharide-based polyelectrolyte multilayer surface coatings can enhance mesenchymal stem cell response to adsorbed growth factors.

Authors:  Jorge Almodóvar; Samantha Bacon; Jarrod Gogolski; John D Kisiday; Matt J Kipper
Journal:  Biomacromolecules       Date:  2010-10-11       Impact factor: 6.988

10.  Enhanced auditory neuron survival following cell-based BDNF treatment in the deaf guinea pig.

Authors:  Lisa N Pettingill; Andrew K Wise; Marilyn S Geaney; Robert K Shepherd
Journal:  PLoS One       Date:  2011-04-15       Impact factor: 3.240
View more
  25 in total

Review 1.  Current Neurogenic and Neuroprotective Strategies to Prevent and Treat Neurodegenerative and Neuropsychiatric Disorders.

Authors:  I M Carvalho; P B Coelho; P C Costa; C S Marques; R S Oliveira; D C Ferreira
Journal:  Neuromolecular Med       Date:  2015-09-15       Impact factor: 3.843

Review 2.  Animal model studies yield translational solutions for cochlear drug delivery.

Authors:  R D Frisina; M Budzevich; X Zhu; G V Martinez; J P Walton; D A Borkholder
Journal:  Hear Res       Date:  2018-05-05       Impact factor: 3.208

3.  Dual Release Carriers for Cochlear Delivery.

Authors:  Sahar Rahmani; Astin M Ross; Tae-Hong Park; Hakan Durmaz; Acacia F Dishman; Diane M Prieskorn; Nathan Jones; Richard A Altschuler; Joerg Lahann
Journal:  Adv Healthc Mater       Date:  2015-07-14       Impact factor: 9.933

4.  Chronic neurotrophin delivery promotes ectopic neurite growth from the spiral ganglion of deafened cochleae without compromising the spatial selectivity of cochlear implants.

Authors:  Thomas G Landry; James B Fallon; Andrew K Wise; Robert K Shepherd
Journal:  J Comp Neurol       Date:  2013-08-15       Impact factor: 3.215

5.  Aminoglycoside Increases Permeability of Osseous Spiral Laminae of Cochlea by Interrupting MMP-2 and MMP-9 Balance.

Authors:  Dengke Li; Jianhe Sun; Lidong Zhao; Weiwei Guo; Wei Sun; Shiming Yang
Journal:  Neurotox Res       Date:  2016-12-22       Impact factor: 3.911

Review 6.  Nanoparticles in the brain: a potential therapeutic system targeted to an early defect observed in many neurodegenerative diseases.

Authors:  Shermali Gunawardena
Journal:  Pharm Res       Date:  2013-04-27       Impact factor: 4.200

7.  Drug delivery to the inner ear.

Authors:  Andrew K Wise; Lisa N Gillespie
Journal:  J Neural Eng       Date:  2012-11-27       Impact factor: 5.379

Review 8.  New molecular therapies for the treatment of hearing loss.

Authors:  Yutian Ma; Andrew K Wise; Robert K Shepherd; Rachael T Richardson
Journal:  Pharmacol Ther       Date:  2019-05-08       Impact factor: 12.310

9.  Nanoformulation of Brain-Derived Neurotrophic Factor with Target Receptor-Triggered-Release in the Central Nervous System.

Authors:  Yuhang Jiang; James M Fay; Chi-Duen Poon; Natasha Vinod; Yuling Zhao; Kristin Bullock; Si Qin; Devika S Manickam; Xiang Yi; William A Banks; Alexander V Kabanov
Journal:  Adv Funct Mater       Date:  2017-12-07       Impact factor: 18.808

Review 10.  Neurotrophic Factors in Parkinson's Disease: Clinical Trials, Open Challenges and Nanoparticle-Mediated Delivery to the Brain.

Authors:  Olesja Bondarenko; Mart Saarma
Journal:  Front Cell Neurosci       Date:  2021-06-02       Impact factor: 5.505
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.