Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Expression of bacterial GshF in Pichia pastoris for glutathione production.

Literature DB >> 22610434

Expression of bacterial GshF in Pichia pastoris for glutathione production.

Abstract

Conventionally, two consecutive enzymatic reactions catalyzed by γ-glutamylcysteine synthetase and glutathione synthetase are most commonly used for glutathione production. Here we demonstrate that bacterial bifunctional GshF can be used for glutathione production in a eukaryotic system without accumulation of the intermediate γ-glutamylcysteine.

Entities: Chemical Species

Mesh：

Substances：

Year: 2012 PMID： 22610434 PMCID： PMC3416392 DOI： 10.1128/AEM.00509-12

Source DB: PubMed Journal: Appl Environ Microbiol ISSN： 0099-2240 Impact factor: 4.792

21 in total

Review 1. Glutathione.

Authors: A Meister; M E Anderson
Journal: Annu Rev Biochem Date: 1983 Impact factor: 23.643

2. Characterization of the bifunctional gamma-glutamate-cysteine ligase/glutathione synthetase (GshF) of Pasteurella multocida.

Authors: Bjorn Vergauwen; Dirk De Vos; Jozef J Van Beeumen
Journal: J Biol Chem Date: 2005-12-08 Impact factor: 5.157

3. A multidomain fusion protein in Listeria monocytogenes catalyzes the two primary activities for glutathione biosynthesis.

Authors: Shubha Gopal; Ilya Borovok; Amos Ofer; Michaela Yanku; Gerald Cohen; Werner Goebel; Jürgen Kreft; Yair Aharonowitz
Journal: J Bacteriol Date: 2005-06 Impact factor: 3.490

Review 4. Glutathione and its role in cellular functions.

Authors: H Sies
Journal: Free Radic Biol Med Date: 1999-11 Impact factor: 7.376

Review 5. Expression of heterologous proteins in Pichia pastoris: a useful experimental tool in protein engineering and production.

Authors: Rachel Daly; Milton T W Hearn
Journal: J Mol Recognit Date: 2005 Mar-Apr Impact factor: 2.137

6. Glutathione biosynthesis in bacteria by bifunctional GshF is driven by a modular structure featuring a novel hybrid ATP-grasp fold.

Authors: Jan Stout; Dirk De Vos; Bjorn Vergauwen; Savvas N Savvides
Journal: J Mol Biol Date: 2011-12-28 Impact factor: 5.469

7. Using Lactococcus lactis for glutathione overproduction.

Authors: Yin Li; Jeroen Hugenholtz; Wilbert Sybesma; Tjakko Abee; Douwe Molenaar
Journal: Appl Microbiol Biotechnol Date: 2004-10-13 Impact factor: 4.813

8. Glutathione synthesis in Streptococcus agalactiae. One protein accounts for gamma-glutamylcysteine synthetase and glutathione synthetase activities.

Authors: Blythe E Janowiak; Owen W Griffith
Journal: J Biol Chem Date: 2005-01-10 Impact factor: 5.157

Review 9. Glutathione: a review on biotechnological production.

Authors: Yin Li; Gongyuan Wei; Jian Chen
Journal: Appl Microbiol Biotechnol Date: 2004-12 Impact factor: 4.813

10. Construction of glutathione-producing strains of Escherichia coli B by recombinant DNA techniques.

Authors: H Gushima; T Miya; K Murata; A Kimura
Journal: J Appl Biochem Date: 1983 Feb-Apr

5 in total

1. Metabolic engineering of Lactococcus lactis for high level accumulation of glutathione and S-adenosyl-L-methionine.

Authors: Chutian Xu; Zhuwei Shi; Jiaqi Shao; Chengkai Yu; Zhinan Xu
Journal: World J Microbiol Biotechnol Date: 2019-11-14 Impact factor: 3.312

2. Functional identification of glutamate cysteine ligase and glutathione synthetase in the marine yeast Rhodosporidium diobovatum.

Authors: Min Kong; Fengjuan Wang; Liuying Tian; Hui Tang; Liping Zhang
Journal: Naturwissenschaften Date: 2017-12-15