Literature DB >> 22610081

Cystosarcoma phyllodes with muscular and lymph node metastasis. Our experience and review of the literature.

Alessandro Sanguinetti1, Giovanni Bistoni, Filippo Calzolari, Roberta Lucchini, Massimo Monacelli, Roberta Triola, Nicola Avenia.   

Abstract

BACKGROUND: Phyllodes tumors are biphasic fibroepithelial neoplasms of the breast. While the surgical management of these relatively uncommon tumors has been addressed in the literature, few reports have commented on the surgical approach to tumors greater than ten centimeters in diameter - the giant phyllodes tumor. CASE REPORT: We report a case of a 45-year-old woman who presented with a large lump in her right breast, involvement of multiple ipsilateral axillary lymph nodes and pectoralis major muscle. Clinical findings and cytologic examination (fine-needle aspiration) were suggestive of cystosarcoma phyllodes and we discuss the techniques utilized for pre-operative diagnosis, tumor removal, and breast reconstruction. A review of the literature on the surgical management of phyllodes tumors was performed.
CONCLUSION: Management of the phyllodes tumor presents the surgeon with unique challenges. The majority of these tumors can be managed by simple mastectomy. In our case clinical findings and cytologic examination (fine-needle aspiration) were suggestive of cystosarcoma phyllodes, for which the patient underwent a modified radical mastectomy. Postoperative radio therapy was given to the loco regional area. KEYWORDS: Immediate reconstruction, Phylloides tumors, Post-operative radio therapy, Radical surgery.

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Year:  2012        PMID: 22610081

Source DB:  PubMed          Journal:  Ann Ital Chir        ISSN: 0003-469X            Impact factor:   0.766


  5 in total

1.  Huge borderline phyllodes breast tumor with repeated recurrences and progression toward more malignant phenotype: a case report and literature review.

Authors:  Yining Wang; Yonglin Zhang; Guanglei Chen; Fangming Liu; Chao Liu; Tiantian Xu; Zhenhai Ma
Journal:  Onco Targets Ther       Date:  2018-11-02       Impact factor: 4.147

2.  Malignant phyllodes tumor of the breast with rapid progression: a case report.

Authors:  Hajime Abe; Atsuko Teramoto; Yumiko Takei; Yoshihito Tanaka; Genichiro Yoneda
Journal:  Surg Case Rep       Date:  2020-12-07

3.  Primitive sarcoma of the breast: new insight on the proper surgical management.

Authors:  Vittorio Pasta; Massimo Monti; Michela Cialini; Massimo Vergine; Paolo Urciuoli; Annunziata Iacovelli; Silvio Rea; Valerio D'Orazi
Journal:  J Exp Clin Cancer Res       Date:  2015-07-30

4.  An 11 kg Phyllodes tumor of the breast in combination with other multiple chronic diseases: Case report and review of the literature.

Authors:  Zhilong Zhao; Jia Zhang; Yuanyuan Chen; Lanwan Shen; Jiansheng Wang
Journal:  Oncol Lett       Date:  2013-05-22       Impact factor: 2.967

5.  Huge Fungating Benign Phyllodes Tumor of Breast.

Authors:  Altaf Hussain Rathore
Journal:  Pak J Med Sci       Date:  2018 May-Jun       Impact factor: 1.088

  5 in total

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