Literature DB >> 22609705

Multimodality treatment of a complex series of parallel pathologies in a 16-year-old male that ultimately leads to bilateral hip arthroplasty surgery: A case report.

Emmet Cullen1, John Quinlan, Esmond Fogarty, Peter Keogh.   

Abstract

INTRODUCTION: Femoral head osteonecrosis is associated with significant sequelae for the patient in the long-term. A combination of factors are thought to contribute to the pathophysiology behind this debilitating disease process. PRESENTATION OF CASE: We report on a 16-year-old adolescent male requiring staged bilateral hybrid hip arthroplasty within 3years of diagnosis of acute lymphoblastic leukaemia that ran a complicated course of multimodality treatment. DISCUSSION: The case examines the literature on femoral head osteonecrosis in this population cohort and the challenge for the orthopaedic surgeon in the management of this increasingly prevalent condition.
CONCLUSION: In a young population cohort, it is important to have arthroplasty surgery as part of the management armamentarium, especially when coupled with complex pathology.
Copyright © 2012 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

Entities:  

Year:  2012        PMID: 22609705      PMCID: PMC3376720          DOI: 10.1016/j.ijscr.2012.04.015

Source DB:  PubMed          Journal:  Int J Surg Case Rep        ISSN: 2210-2612


  15 in total

1.  Osteonecrosis in children treated for acute lymphoblastic leukemia: a magnetic resonance imaging study after treatment.

Authors:  A E Ojala; F P Lanning; E Pääkkö; B M Lanning
Journal:  Med Pediatr Oncol       Date:  1997-10

2.  Radiation-induced osteonecrosis of the hips following genital-preserving surgery and chemoradiotherapy.

Authors:  John F Quinlan; John North; Deborah A Clarke; David P Gwynne-Jones
Journal:  N Z Med J       Date:  2009-06-19

3.  Slipping of the upper femoral epiphyses in patients with intracranial tumours causing hypopituitarism and chiasmal compression.

Authors:  F W Heatley; R H Greenwood; D L Boase
Journal:  J Bone Joint Surg Br       Date:  1976-05

4.  Case report: paediatric radiotherapy--the avoidance of late radiation damage to the growing hip.

Authors:  C J Irwin; E Thomson; P N Plowman
Journal:  Br J Radiol       Date:  1993-04       Impact factor: 3.039

5.  Osteonecrosis as a complication of treating acute lymphoblastic leukemia in children: a report from the Children's Cancer Group.

Authors:  L A Mattano; H N Sather; M E Trigg; J B Nachman
Journal:  J Clin Oncol       Date:  2000-09-15       Impact factor: 44.544

Review 6.  Relationship between systemic corticosteroids and osteonecrosis.

Authors:  K L Gebhard; H I Maibach
Journal:  Am J Clin Dermatol       Date:  2001       Impact factor: 7.403

7.  Bone marrow magnetic resonance studies in childhood leukemia. Evaluation of osteonecrosis.

Authors:  R Pieters; A I van Brenk; A J Veerman; A H van Amerongen; T E van Zanten; R P Golding
Journal:  Cancer       Date:  1987-12-15       Impact factor: 6.860

8.  Osteonecrosis: An emerging complication of intensive chemotherapy for childhood acute lymphoblastic leukemia.

Authors:  Maurizio Aricò; Marie France Pinta Boccalatte; Daniela Silvestri; Elena Barisone; Chiara Messina; Robert Chiesa; Nicola Santoro; Paolo Tamaro; Alma Lippi; Domenico Gallisai; Giuseppe Basso; Giulio De Rossi
Journal:  Haematologica       Date:  2003-07       Impact factor: 9.941

Review 9.  Osteonecrosis of the hip: management in the 21st century.

Authors:  Jay R Lieberman; Daniel J Berry; Michael A Mont; Roy K Aaron; John J Callaghan; Amar D Rajadhyaksha; James R Urbaniak
Journal:  Instr Course Lect       Date:  2003

10.  Trends in survival for childhood cancer in Britain diagnosed 1971-85.

Authors:  C A Stiller; K J Bunch
Journal:  Br J Cancer       Date:  1990-11       Impact factor: 7.640

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