OBJECTIVE: To examine the validity of multi-fiber muscle velocity recovery cycles (VRCs) recorded by direct muscle stimulation with submaximal stimuli. METHODS: VRCs were recorded from tibialis anterior muscle in normal volunteers with 1, 2 and 5 conditioning stimuli. Recordings were made with 6 different amplitudes of conditioning stimuli. Recordings were also made with two recording electrodes, at least 15mm apart. RESULTS: Muscle VRCs in 6 subjects were not significantly different for conditioning stimuli between 80% and 150% of test stimulus amplitude. When recorded at two sites in 9 subjects, VRCs were similar when estimated over the shorter distance, the longer distance, and from the conduction time between the two electrodes. CONCLUSIONS: Multi-fiber muscle VRCs can be reliably recorded with a single recording electrode and with equal amplitude conditioning and test stimuli. SIGNIFICANCE: Clinical neurophysiologists can be assured that this new method of testing muscle membrane properties provides valid and robust measurements on normal muscles.
OBJECTIVE: To examine the validity of multi-fiber muscle velocity recovery cycles (VRCs) recorded by direct muscle stimulation with submaximal stimuli. METHODS: VRCs were recorded from tibialis anterior muscle in normal volunteers with 1, 2 and 5 conditioning stimuli. Recordings were made with 6 different amplitudes of conditioning stimuli. Recordings were also made with two recording electrodes, at least 15mm apart. RESULTS: Muscle VRCs in 6 subjects were not significantly different for conditioning stimuli between 80% and 150% of test stimulus amplitude. When recorded at two sites in 9 subjects, VRCs were similar when estimated over the shorter distance, the longer distance, and from the conduction time between the two electrodes. CONCLUSIONS: Multi-fiber muscle VRCs can be reliably recorded with a single recording electrode and with equal amplitude conditioning and test stimuli. SIGNIFICANCE: Clinical neurophysiologists can be assured that this new method of testing muscle membrane properties provides valid and robust measurements on normal muscles.
Authors: S Veronica Tan; Werner J Z'graggen; Delphine Boërio; Christopher Turner; Michael G Hanna; Hugh Bostock Journal: Muscle Nerve Date: 2016-05-24 Impact factor: 3.217
Authors: Karin A Ackermann; Hugh Bostock; Lukas Brander; Ralph Schröder; Siamak Djafarzadeh; Daniel Tuchscherer; Stephan M Jakob; Jukka Takala; Werner J Z'Graggen Journal: Crit Care Date: 2014-08-22 Impact factor: 9.097