Literature DB >> 22607793

Old antibiotics target TB with a new trick.

Alfred J Zullo1, Sunhee Lee.   

Abstract

Autophagy is now recognized as a cellular defense mechanism that can restrict the growth of Mycobacterium tuberculosis (Mtb). In this issue of Cell Host & Microbe, Kim et al. (2012) demonstrate that antibiotics routinely used to treat Mtb infection elicit a host autophagy response critical for bacterial clearance.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22607793     DOI： 10.1016/j.chom.2012.05.002

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN： 1931-3128            Impact factor:   21.023


  5 in total

Review 1.  Targeted pulmonary delivery of inducers of host macrophage autophagy as a potential host-directed chemotherapy of tuberculosis.

Authors:  Anuradha Gupta; Amit Misra; Vojo Deretic
Journal:  Adv Drug Deliv Rev       Date:  2016-01-29       Impact factor: 15.470

Review 2.  Targeting Autophagy as a Strategy for Developing New Vaccines and Host-Directed Therapeutics Against Mycobacteria.

Authors:  Emily J Strong; Sunhee Lee
Journal:  Front Microbiol       Date:  2021-01-14       Impact factor: 6.064

Review 3.  Mycobacterial signaling through toll-like receptors.

Authors:  Joyoti Basu; Dong-Min Shin; Eun-Kyeong Jo
Journal:  Front Cell Infect Microbiol       Date:  2012-11-23       Impact factor: 5.293

4.  Mammalian target of Rapamycin inhibition and mycobacterial survival are uncoupled in murine macrophages.

Authors:  Alfred J Zullo; Kristen L Jurcic Smith; Sunhee Lee
Journal:  BMC Biochem       Date:  2014-02-14       Impact factor: 4.059

Review 5.  Modulation of Host Autophagy during Bacterial Infection: Sabotaging Host Munitions for Pathogen Nutrition.

Authors:  Pedro Escoll; Monica Rolando; Carmen Buchrieser
Journal:  Front Immunol       Date:  2016-03-03       Impact factor: 7.561
  5 in total

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