Literature DB >> 22605809

Antifreeze on a freezing morning: ethylene glycol poisoning in a 2-year-old.

Gayle Hann1, Dana Duncan, Gopakumar Sudhir, Peter West, Dalbir Sohi.   

Abstract

This case report describes the presentation and management of a 2-year-old child who ingested a potentially fatal amount of ethylene glycol (EG). There are few published cases worldwide of EG poisoning in children managed with fomepizole. All cases described in the literature were managed in a paediatric intensive care unit. In this case, the child presented irritable, pale and confused with high anion gap metabolic acidosis. As there were no paediatric intensive care beds available in the region, the child was successfully managed in a high dependency area in our district general hospital. The child fully recovered and was discharged home in 7 days. The authors believe that multi-disciplinary team management and the use of fomepizole contributed to the positive outcome and this case raised many useful learning points.

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Year:  2012        PMID: 22605809      PMCID: PMC3316811          DOI: 10.1136/bcr.07.2011.4509

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

1.  Ethylene glycol toxicity: closing in on rational, evidence-based treatment.

Authors:  W A Watson
Journal:  Ann Emerg Med       Date:  2000-08       Impact factor: 5.721

Review 2.  Acute poisoning: understanding 90% of cases in a nutshell.

Authors:  S L Greene; P I Dargan; A L Jones
Journal:  Postgrad Med J       Date:  2005-04       Impact factor: 2.401

3.  Nystagmus secondary to fomepizole administration in a pediatric patient.

Authors:  J G Benitez; B Swanson-Biearman; E P Krenzelok
Journal:  J Toxicol Clin Toxicol       Date:  2000

Review 4.  Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings.

Authors:  Jeffrey Brent
Journal:  Clin Toxicol (Phila)       Date:  2010-06       Impact factor: 4.467

Review 5.  Novel therapies for ethylene glycol intoxication.

Authors:  J F Wiley
Journal:  Curr Opin Pediatr       Date:  1999-06       Impact factor: 2.856

6.  Treatment of severe pediatric ethylene glycol intoxication without hemodialysis.

Authors:  E Martin Caravati; Heather L Heileson; Michael Jones
Journal:  J Toxicol Clin Toxicol       Date:  2004
  6 in total
  2 in total

1.  Successful Resuscitation of a Patient with Life-Threatening Metabolic Acidosis by Hemodialysis: A Case of Ethylene Glycol Intoxication.

Authors:  Ikuyo Narita; Michiko Shimada; Norio Nakamura; Reiichi Murakami; Takeshi Fujita; Wakako Fukuda; Hirofumi Tomita
Journal:  Case Rep Nephrol       Date:  2017-07-25

2.  Loss of consciousness in a little traveler.

Authors:  Anahita Alizadeh; Forough Rakhshanizadeh
Journal:  Caspian J Intern Med       Date:  2021
  2 in total

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