Literature DB >> 22605597

Pemphigus vulgaris--a report of three cases.

Harshkant P Gharote1, Preeti P Nair, Sowmya Kasetty, Shaji Thomas, Abhay Kulkarni.   

Abstract

Pemphigus vulgaris (PV) is a potentially life-threatening illness that manifests in the mouth and on skin. In a majority of patients it affects the oral mucosa and is sometimes difficult to diagnose when only mucosal involvement is present. In an attempt to highlight the proper treatment plan of this potentially fatal disorder, the authors document a report of three cases. These patients were prescribed conventional steroids which brought about partial relief but early recurrence with discontinuation of the drug. Subsequent management of these patients with azathioprine along with corticosteroids improved the outcome of the disease with longer remission periods. In this case series, the steroid sparing effect of azathioprine was achieved successfully and hence needs to be considered as a primary drug in management of PV.

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Year:  2012        PMID: 22605597      PMCID: PMC3316867          DOI: 10.1136/bcr.11.2011.5239

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  14 in total

1.  Oral pemphigus vulgaris preceding cutaneous lesions: recognition and diagnosis.

Authors:  D Sirois; J E Leigh; T P Sollecito
Journal:  J Am Dent Assoc       Date:  2000-08       Impact factor: 3.634

2.  Guidelines for the management of pemphigus vulgaris.

Authors:  K E Harman; S Albert; M M Black
Journal:  Br J Dermatol       Date:  2003-11       Impact factor: 9.302

3.  A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of pemphigus.

Authors:  Stefan Beissert; Thomas Werfel; Uta Frieling; Markus Böhm; Michael Sticherling; Rudolf Stadler; Detlev Zillikens; Berthold Rzany; Nicolas Hunzelmann; Michael Meurer; Harald Gollnick; Thomas Ruzicka; Hans Pillekamp; Volker Junghans; Thomas A Luger
Journal:  Arch Dermatol       Date:  2006-11

4.  Pemphigus vulgaris in oral cavity: clinical analysis of 71 cases.

Authors:  Thorakkal Shamim; Vengal Ipe Varghese; Pallikandi Maliyekkal Shameena; Sivasankar Sudha
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2008-10-01

Review 5.  Pemphigus in India.

Authors:  Amrinder J Kanwar; Dipankar De
Journal:  Indian J Dermatol Venereol Leprol       Date:  2011 Jul-Aug       Impact factor: 2.545

6.  Pemphigus in Israel--an epidemiologic analysis of cases in search of risk factors.

Authors:  Yonit Wohl; Sarah Brenner
Journal:  Isr Med Assoc J       Date:  2003-06       Impact factor: 0.892

7.  Treatment of pemphigus vulgaris and pemphigus foliaceus with mycophenolate mofetil.

Authors:  Daniel Mimouni; Grant J Anhalt; Deborah L Cummins; David J Kouba; Jennifer E Thorne; H Carlos Nousari
Journal:  Arch Dermatol       Date:  2003-06

8.  Pulse intravenous cyclophosphamide therapy in pemphigus.

Authors:  M E Fleischli; R H Valek; A G Pandya
Journal:  Arch Dermatol       Date:  1999-01

9.  Mycophenolate is effective in the treatment of pemphigus vulgaris.

Authors:  A H Enk; J Knop
Journal:  Arch Dermatol       Date:  1999-01

10.  Pemphigus vulgaris.

Authors:  Sandhya Tamgadge; Avinash Tamgadge; Daivat M Bhatt; Sudhir Bhalerao; Treville Pereira
Journal:  Contemp Clin Dent       Date:  2011-04
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