Literature DB >> 22605593

Haloperidol induced obsessive compulsive symptom (OCS) in a patient with learning disability and bipolar affective disorder.

Inam Ulhaq1, Adam Abba-Aji.   

Abstract

In this case report, a patient with severe learning disability and bipolar affective disorder developed de-nova obsessive compulsive symptom (OCS) with haloperidol, a conventional antipsychotic medication and the OCS stopped with stopping haloperidol. Antipsychotics are recommended and used as augmentation therapy in resistant cases of obsessive compulsive disorder. Although second generation antipsychotics have been reported to have induced OCS but haloperidol, which is a first generation antipsychotic has not been implicated in OCS induction. There is no published report of antipsychotics induced OCS in learning disability population. Clinician should be aware of this potential side effect of haloperidol.

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Year:  2012        PMID: 22605593      PMCID: PMC3316822          DOI: 10.1136/bcr.11.2011.5161

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  13 in total

Review 1.  A review of antipsychotics in the treatment of obsessive compulsive disorder.

Authors:  Naomi A Fineberg; Tim M Gale; Thanusha Sivakumaran
Journal:  J Psychopharmacol       Date:  2005-10-04       Impact factor: 4.153

2.  Development of transient obsessive-compulsive symptoms during treatment with clozapine.

Authors:  V J Patil
Journal:  Am J Psychiatry       Date:  1992-02       Impact factor: 18.112

3.  Risperidone may worsen fluoxetine-treated OCD.

Authors:  C Andrade
Journal:  J Clin Psychiatry       Date:  1998-05       Impact factor: 4.384

4.  Chlorpromazine and obsessive-compulsive symptoms.

Authors:  R H Howland
Journal:  Am J Psychiatry       Date:  1996-11       Impact factor: 18.112

5.  Haloperidol addition in fluvoxamine-refractory obsessive-compulsive disorder. A double-blind, placebo-controlled study in patients with and without tics.

Authors:  C J McDougle; W K Goodman; J F Leckman; N C Lee; G R Heninger; L H Price
Journal:  Arch Gen Psychiatry       Date:  1994-04

6.  Treatment of delusional disorders with clozapine.

Authors:  P F Buckley; M Sajatovic; H Y Meltzer
Journal:  Am J Psychiatry       Date:  1994-09       Impact factor: 18.112

7.  Obsessive-compulsive symptoms and clozapine.

Authors:  S M Dursun; M A Reveley
Journal:  Br J Psychiatry       Date:  1994-08       Impact factor: 9.319

8.  The 5-HT2 receptor profiles of antipsychotics in the pathogenesis of obsessive-compulsive symptoms in schizophrenia.

Authors:  Sung-Wan Kim; Il-Seon Shin; Jae-Min Kim; Tak Youn; Su-Jin Yang; Michael Y Hwang; Jin-Sang Yoon
Journal:  Clin Neuropharmacol       Date:  2009 Jul-Aug       Impact factor: 1.592

Review 9.  Psychiatric comorbidities and schizophrenia.

Authors:  Peter F Buckley; Brian J Miller; Douglas S Lehrer; David J Castle
Journal:  Schizophr Bull       Date:  2008-11-14       Impact factor: 9.306

10.  Emergence of obsessive compulsive symptoms during treatment with clozapine.

Authors:  R W Baker; K N Chengappa; J W Baird; S Steingard; M A Christ; N R Schooler
Journal:  J Clin Psychiatry       Date:  1992-12       Impact factor: 4.384

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