Literature DB >> 2259891

Attempt to show inhibition by oxygen in the modifying factor assay.

J R Archer1, A Claxson, A Edwards, P W Thompson.   

Abstract

An Australian laboratory has demonstrated that antibodies to certain strains of enteric bacteria react with cells from HLA-B27-positive patients with a 'modifying factor' (MF) from these bacteria. These observations have proved difficult to reproduce. We investigated the possibility that oxygen inhibits the test by blocking B27, but we were unable to obtain consistent positive results.

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Year:  1990        PMID: 2259891     DOI: 10.3109/03009749009097062

Source DB:  PubMed          Journal:  Scand J Rheumatol Suppl        ISSN: 0301-3847


  1 in total

1.  Failure of the serological determination of HLA-B27 due to antigen masking in patients with ankylosing spondylitis.

Authors:  J Neumüller; M Fischer; R Eberl
Journal:  Rheumatol Int       Date:  1993       Impact factor: 2.631

  1 in total

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