Literature DB >> 2259873

Treatment of bacterial vaginosis in pregnancy with a lactate gel.

E Holst1, A Brandberg.   

Abstract

10 pregnant women with bacterial vaginosis were treated vaginally with a low-pH lactate gel intermittently during 6 weeks. Reappearance of a lactobacillus-dominated vaginal flora was observed after a few days treatment in all patients. All women experienced a subjective disappearance of abnormal vaginal discharge and malodour. This local treatment restores the normal vaginal acidity and facilitates recolonization with lactobacilli. It may be preferable to oral antimicrobial therapy, especially during pregnancy.

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Year:  1990        PMID: 2259873     DOI: 10.3109/00365549009027109

Source DB:  PubMed          Journal:  Scand J Infect Dis        ISSN: 0036-5548


  8 in total

1.  A pilot clinical trial comparing an acid-buffering formulation (ACIDFORM gel) with metronidazole gel for the treatment of symptomatic bacterial vaginosis.

Authors:  Jose A Simoes; Luis G Bahamondes; Rodrigo P S Camargo; Valeria M N Alves; Lourens J D Zaneveld; Donald P Waller; Jill Schwartz; Marianne M Callahan; Christine K Mauck
Journal:  Br J Clin Pharmacol       Date:  2006-02       Impact factor: 4.335

Review 2.  Antibiotics for treating bacterial vaginosis in pregnancy.

Authors:  H M McDonald; P Brocklehurst; A Gordon
Journal:  Cochrane Database Syst Rev       Date:  2007-01-24

Review 3.  Bacterial vaginosis.

Authors:  C A Spiegel
Journal:  Clin Microbiol Rev       Date:  1991-10       Impact factor: 26.132

4.  Estimation of the Incidence of Bacterial Vaginosis and other Vaginal Infections and its Consequences on Maternal/Fetal Outcome in Pregnant Women Attending an Antenatal Clinic in a Tertiary Care Hospital in North India.

Authors:  Indu Lata; Yashodhara Pradeep; Amita Jain
Journal:  Indian J Community Med       Date:  2010-04

5.  Bacterial vaginosis and vaginal microorganisms in idiopathic premature labor and association with pregnancy outcome.

Authors:  E Holst; A R Goffeng; B Andersch
Journal:  J Clin Microbiol       Date:  1994-01       Impact factor: 5.948

6.  Effect of lactic acid suppositories compared with oral metronidazole and placebo in bacterial vaginosis: a randomised clinical trial.

Authors:  A J Boeke; J H Dekker; J T van Eijk; P J Kostense; P D Bezemer
Journal:  Genitourin Med       Date:  1993-10

Review 7.  Lactobacillus species as biomarkers and agents that can promote various aspects of vaginal health.

Authors:  Mariya I Petrova; Elke Lievens; Shweta Malik; Nicole Imholz; Sarah Lebeer
Journal:  Front Physiol       Date:  2015-03-25       Impact factor: 4.566

8.  Rationale and Safety Assessment of a Novel Intravaginal Drug-Delivery System with Sustained DL-Lactic Acid Release, Intended for Long-Term Protection of the Vaginal Microbiome.

Authors:  Hans Verstraelen; Chris Vervaet; Jean-Paul Remon
Journal:  PLoS One       Date:  2016-04-19       Impact factor: 3.240

  8 in total

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