Literature DB >> 22596320

The fate and future of patents on human genes and genetic diagnostic methods.

Isabelle Huys1, Gert Matthijs, Geertrui Van Overwalle.   

Abstract

Since the 1970s, patents on human genes and genetic diagnostic methods have been granted under the assumption that they stimulate the development of diagnostic methods and therapeutic products. However, the principles and practices of patenting vary between jurisdictions. Do patent holders, researchers, clinicians and patients really benefit from this heterogeneous patent system? We discuss the problems that result from the current system and suggest how they might be solved by altering the way in which patents are granted and/or licensed.

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Year:  2012        PMID: 22596320     DOI: 10.1038/nrg3255

Source DB:  PubMed          Journal:  Nat Rev Genet        ISSN: 1471-0056            Impact factor:   53.242


  24 in total

1.  The gene patenting controversy: a convergence of law, economic interests, and ethics.

Authors:  D J Kevles; A Berkowitz
Journal:  Brooklyn Law Rev       Date:  2001

2.  Debunking the myth that whole-genome sequencing infringes thousands of gene patents.

Authors:  Christopher M Holman
Journal:  Nat Biotechnol       Date:  2012-03-07       Impact factor: 54.908

3.  Evidence and anecdotes: an analysis of human gene patenting controversies.

Authors:  Timothy Caulfield; Robert M Cook-Deegan; F Scott Kieff; John P Walsh
Journal:  Nat Biotechnol       Date:  2006-09       Impact factor: 54.908

Review 4.  Genomics, health care, and society.

Authors:  Kathy L Hudson
Journal:  N Engl J Med       Date:  2011-09-15       Impact factor: 91.245

5.  Patently unpatentable: implications of the Myriad court decision on genetic diagnostics.

Authors:  Mildred Cho
Journal:  Trends Biotechnol       Date:  2010-11       Impact factor: 19.536

6.  The dangers of diagnostic monopolies.

Authors:  Robert Cook-Deegan; Subhashini Chandrasekharan; Misha Angrist
Journal:  Nature       Date:  2009-03-26       Impact factor: 49.962

7.  The impact of human gene patents on genetic testing in the United Kingdom.

Authors:  Naomi Hawkins
Journal:  Genet Med       Date:  2011-04       Impact factor: 8.822

Review 8.  Models for facilitating access to patents on genetic inventions.

Authors:  Geertrui Van Overwalle; Esther van Zimmeren; Birgit Verbeure; Gert Matthijs
Journal:  Nat Rev Genet       Date:  2006-02       Impact factor: 53.242

9.  Gene patents and personalized medicine - what lies ahead?

Authors:  Subhashini Chandrasekharan; Robert Cook-Deegan
Journal:  Genome Med       Date:  2009-09-28       Impact factor: 11.117

10.  Commercialization, patenting and genomics: researcher perspectives.

Authors:  Cj Murdoch; Timothy Caulfield
Journal:  Genome Med       Date:  2009-02-19       Impact factor: 11.117

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  11 in total

1.  Are the gene-patent storm clouds dissipating? A global snapshot.

Authors:  Johnathon Liddicoat; Tess Whitton; Dianne Nicol
Journal:  Nat Biotechnol       Date:  2015-04       Impact factor: 54.908

2.  The European BRCA patent oppositions and appeals: coloring inside the lines.

Authors:  Gert Matthijs; Isabelle Huys; Geertrui Van Overwalle; Dominique Stoppa-Lyonnet
Journal:  Nat Biotechnol       Date:  2013-08       Impact factor: 54.908

3.  Looking back and moving forward: an historical perspective from laboratory genetic counselors.

Authors:  Lindsay H Zetzsche; Katrina E Kotzer; Karen E Wain
Journal:  J Genet Couns       Date:  2013-11-12       Impact factor: 2.537

Review 4.  Do recent US Supreme Court rulings on patenting of genes and genetic diagnostics affect the practice of genetic screening and diagnosis in prenatal and reproductive care?

Authors:  Subhashini Chandrasekharan; Amy L McGuire; Ignatia B Van den Veyver
Journal:  Prenat Diagn       Date:  2014-07-31       Impact factor: 3.050

5.  After Myriad, what makes a gene patent claim 'markedly different' from nature?

Authors:  Mateo Aboy; Johnathon Liddicoat; Kathleen Liddell; Matthew Jordan; Cristina Crespo
Journal:  Nat Biotechnol       Date:  2017-09-11       Impact factor: 54.908

6.  Patient-controlled encrypted genomic data: an approach to advance clinical genomics.

Authors:  Yannis J Trakadis
Journal:  BMC Med Genomics       Date:  2012-07-20       Impact factor: 3.063

7.  Gene patents still alive and kicking: their impact on provision of genetic testing for long QT syndrome in the Canadian public health-care system.

Authors:  Sarah E Ali-Khan; E Richard Gold
Journal:  Genet Med       Date:  2017-05-11       Impact factor: 8.822

8.  Absolute and relative quantification of multiplex DNA assays based on an elemental labeling strategy.

Authors:  Guojun Han; Sichun Zhang; Zhi Xing; Xinrong Zhang
Journal:  Angew Chem Int Ed Engl       Date:  2012-12-12       Impact factor: 15.336

Review 9.  Ethics education for clinician-researchers in genetics: The combined approach.

Authors:  Ma'n Zawati; Eliza Cohen; David Parry; Denise Avard; David Syncox
Journal:  Appl Transl Genom       Date:  2014-12-16

Review 10.  Eteplirsen in the treatment of Duchenne muscular dystrophy.

Authors:  Kenji Rowel Q Lim; Rika Maruyama; Toshifumi Yokota
Journal:  Drug Des Devel Ther       Date:  2017-02-28       Impact factor: 4.162

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