| Literature DB >> 22595813 |
Changhao Wang1, Yinghao Li, Guoqing Jia, Yan Liu, Shengmei Lu, Can Li.
Abstract
A human telomeric G-quadruplex (G4DNA) metalloenzyme, assembled with G4DNA and Cu(2+) ions, can catalyze the enantioselective Friedel-Crafts (F-C) reaction in water with good enantioselectivity (up to 75% ee). Furthermore, we found that the absolute configuration and the enantioselectivity of the product largely depend on the conformation and the sequence of G4DNA.Entities:
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Year: 2012 PMID： 22595813 DOI： 10.1039/c2cc31320k
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222