Literature DB >> 22595572

Evaluation of Surgisis for patch repair of abdominal wall defects in children.

Alana Beres1, Emily R Christison-Lagay, Rodrigo L P Romao, Jacob C Langer.   

Abstract

BACKGROUND: Abdominal wall defects in children are not always amenable to primary repair and may require a patch. The ideal material has yet to be established. We sought to evaluate our experience using the bioabsorbable material Surgisis (Cook Surgical, Bloomington, IN) for abdominal closure.
METHODS: A retrospective chart review of abdominal wall defects repaired with Surgisis in our institution from 2000 to 2010 was performed. Data extracted included cause of defect, age at operation, possibility of skin coverage, recurrence, length of follow-up, and rate of wound infection.
RESULTS: Thirteen patients were identified. Cause of defect was gastroschisis (n = 2), ventral hernia after diaphragmatic hernia repair (n = 2), and omphalocele (n = 9). At median follow-up of 60 months (range, 10-90), 5 (38%) of 13 patients recurred, and 1 patient recurred twice. All recurrences required subsequent patch closure. Six instances of wound infection required antibiotics. None required patch removal. There was a trend toward more frequent recurrence among infants undergoing patch repair (3/4 recurrences in this group) than neonates (1/4 recurrences) or children older than 18 months (1/5 recurrences).
CONCLUSION: Our data suggest that Surgisis is moderately successful in the repair of pediatric abdominal wall defects. We noted a trend toward a higher recurrence rate in infants. Further studies investigating timing of repair and alternative biosynthetic materials are warranted.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2012        PMID: 22595572     DOI: 10.1016/j.jpedsurg.2012.01.046

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  5 in total

1.  Reverse Tissue Expansion in Gastroschisis: What to do if the Defect is too large to close after Silo Removal?

Authors:  Boma T Adikibi; Stuart O'Toole
Journal:  J Neonatal Surg       Date:  2014-10-20

2.  Effectiveness and properties of the biological prosthesis Permacol™ in pediatric surgery: A large single center experience.

Authors:  Claudia Filisetti; Sara Costanzo; Federica Marinoni; Claudio Vella; Catherine Klercy; Giovanna Riccipetitoni
Journal:  Ann Med Surg (Lond)       Date:  2016-03-11

Review 3.  Scaffolding Strategies for Tissue Engineering and Regenerative Medicine Applications.

Authors:  Sandra Pina; Viviana P Ribeiro; Catarina F Marques; F Raquel Maia; Tiago H Silva; Rui L Reis; J Miguel Oliveira
Journal:  Materials (Basel)       Date:  2019-06-05       Impact factor: 3.623

4.  The Use of Acellular Dermal Matrix (Integra Single Layer) for the Correction of Malformative Chest Wall Deformities: First Case Series Reported.

Authors:  Carlos Delgado-Miguel; Miriam Miguel-Ferrero; Antonio Muñoz-Serrano; Mercedes Díaz; Juan Carlos López-Gutiérrez; Carlos De la Torre
Journal:  Surg J (N Y)       Date:  2022-08-16

5.  Repair of Postoperative Abdominal Hernia in a Child with Congenital Omphalocele Using Porcine Dermal Matrix.

Authors:  V Lambropoulos; E Mylona; V Mouravas; C Tsakalidis; I Spyridakis; G Mitsiakos; P Karagianni
Journal:  Case Rep Med       Date:  2016-03-24
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.