Massimo Del Fabbro1, Valentina Ceresoli, Alessandra Lolato, Silvio Taschieri. 1. IRCCS Galeazzi Orthopaedic Institute, Dental Clinic, Centro di Ricerca per la Salute Orale (CRSO), Department of Health Technologies, University of Milan, Milan, Italy. massimo.delfabbro@unimi.it
Abstract
INTRODUCTION: Control of postoperative discomfort might enhance the patient's quality of life and treatment acceptance. The aim of the present randomized single-blind study was to evaluate whether the use of platelet concentrate during endodontic surgery might have a favorable impact on pain and other factors related to patient's quality of life during the first week after surgery. METHODS:Eighteen patients with periapical lesion were treated with modern endodontic surgical procedure (control group). In another 18 patients, in adjunct to surgical procedure, platelet concentrate was applied on the root end in liquid form, within the bone defect in clot form, and over the suture in liquid form (test group). All patients completed a questionnaire for evaluation of main symptoms and daily activities during the first week after surgery. The outcomes of the questionnaires of the 2 groups were statistically compared. RESULTS: The test group showed significantly less pain and swelling, fewer analgesics taken, and improved functional activities as compared with the control group. CONCLUSIONS: The adjunct of platelet concentrate to the endodontic surgical procedure produced significant beneficial effect to patients' quality of life during the early postoperative stage.
RCT Entities:
INTRODUCTION: Control of postoperative discomfort might enhance the patient's quality of life and treatment acceptance. The aim of the present randomized single-blind study was to evaluate whether the use of platelet concentrate during endodontic surgery might have a favorable impact on pain and other factors related to patient's quality of life during the first week after surgery. METHODS: Eighteen patients with periapical lesion were treated with modern endodontic surgical procedure (control group). In another 18 patients, in adjunct to surgical procedure, platelet concentrate was applied on the root end in liquid form, within the bone defect in clot form, and over the suture in liquid form (test group). All patients completed a questionnaire for evaluation of main symptoms and daily activities during the first week after surgery. The outcomes of the questionnaires of the 2 groups were statistically compared. RESULTS: The test group showed significantly less pain and swelling, fewer analgesics taken, and improved functional activities as compared with the control group. CONCLUSIONS: The adjunct of platelet concentrate to the endodontic surgical procedure produced significant beneficial effect to patients' quality of life during the early postoperative stage.
Authors: Nastaran Meschi; Steffen Fieuws; Anke Vanhoenacker; Olaf Strijbos; Dominique Van der Veken; Constantinus Politis; Paul Lambrechts Journal: Clin Oral Investig Date: 2018-03-09 Impact factor: 3.573
Authors: Lorenzo Drago; Monica Bortolin; Christian Vassena; Carlo L Romanò; Silvio Taschieri; Massimo Del Fabbro Journal: PLoS One Date: 2014-09-18 Impact factor: 3.240