Literature DB >> 22595016

The effects of irrigation on outcomes in cases of perforated appendicitis in children.

Joseph E Hartwich1, Richard F Carter, Luke Wolfe, Michael Goretsky, Kirk Heath, Shawn D St Peter, David A Lanning.   

Abstract

INTRODUCTION: Appendicitis is the most common indication for urgent abdominal operation in children. Approximately 20%-30% of patients will have a perforation at operation. Intra-abdominal abscess after appendectomy is reported in 3%-20% of patients and adds significantly to hospital stay with increased morbidity and overall cost. Surgical dogma has long advocated for irrigation in the setting of gross pus to prevent abscess formation.
METHODS: Following IRB approval, data were retrospectively collected for children who had undergone appendectomy for perforated appendicitis at one of two children's hospitals over the course of 5 y. Perforation was determined by review of operative notes. All patients had free fluid in their peritoneal cavity evacuated by suction, whereas some of the patients also had their peritoneal cavity irrigated with normal saline. Postoperative intra-abdominal abscess rates were determined based on clinical symptoms and confirmatory radiologic studies.
RESULTS: There were 99 patients in the suction-only group and 139 in the irrigation group. Standard demographics were relatively similar between the two groups. There were significantly lower rates of intra-abdominal abscess formation (4.0% versus 17.2%, P = 0.002) and wound infection (1.0% versus 8.6%, P = 0.003) in the suction-only group compared with the irrigation group. We further analyzed abscess rates by surgical treatment, either laparoscopic or open appendectomy. There were 85 patients in the laparoscopic group and 152 patients in the open appendectomy group. In this subgroup analysis, there were also significantly lower rates of abscess formation in patients treated with suction only compared with irrigation in the laparoscopic (3.5% versus 18.8%, P = 0.012) and open appendectomy groups (4.2% versus 16.3%, P = 0.036).
CONCLUSIONS: Results of this retrospective review indicate that a suction-only approach significantly decreased rates of abscess formation and wound infections compared to irrigation in cases of perforated appendicitis in children.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22595016     DOI: 10.1016/j.jss.2012.04.043

Source DB:  PubMed          Journal:  J Surg Res        ISSN: 0022-4804            Impact factor:   2.192


  9 in total

1.  Risk factors for intra-abdominal abscess following laparoscopic appendectomy for acute appendicitis: a retrospective cohort study on 2076 patients.

Authors:  Dario Tartaglia; Lorenzo Maria Fatucchi; Alessio Mazzoni; Mario Miccoli; Lorenzo Piccini; Marsia Pucciarelli; Salomone Di Saverio; Federico Coccolini; Massimo Chiarugi
Journal:  Updates Surg       Date:  2020-04-27

Review 2.  WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections.

Authors:  Massimo Sartelli; Federico Coccolini; Yoram Kluger; Ervis Agastra; Fikri M Abu-Zidan; Ashraf El Sayed Abbas; Luca Ansaloni; Abdulrashid Kayode Adesunkanmi; Boyko Atanasov; Goran Augustin; Miklosh Bala; Oussama Baraket; Suman Baral; Walter L Biffl; Marja A Boermeester; Marco Ceresoli; Elisabetta Cerutti; Osvaldo Chiara; Enrico Cicuttin; Massimo Chiarugi; Raul Coimbra; Elif Colak; Daniela Corsi; Francesco Cortese; Yunfeng Cui; Dimitris Damaskos; Nicola De' Angelis; Samir Delibegovic; Zaza Demetrashvili; Belinda De Simone; Stijn W de Jonge; Sameer Dhingra; Stefano Di Bella; Francesco Di Marzo; Salomone Di Saverio; Agron Dogjani; Therese M Duane; Mushira Abdulaziz Enani; Paola Fugazzola; Joseph M Galante; Mahir Gachabayov; Wagih Ghnnam; George Gkiokas; Carlos Augusto Gomes; Ewen A Griffiths; Timothy C Hardcastle; Andreas Hecker; Torsten Herzog; Syed Mohammad Umar Kabir; Aleksandar Karamarkovic; Vladimir Khokha; Peter K Kim; Jae Il Kim; Andrew W Kirkpatrick; Victor Kong; Renol M Koshy; Igor A Kryvoruchko; Kenji Inaba; Arda Isik; Katia Iskandar; Rao Ivatury; Francesco M Labricciosa; Yeong Yeh Lee; Ari Leppäniemi; Andrey Litvin; Davide Luppi; Gustavo M Machain; Ronald V Maier; Athanasios Marinis; Cristina Marmorale; Sanjay Marwah; Cristian Mesina; Ernest E Moore; Frederick A Moore; Ionut Negoi; Iyiade Olaoye; Carlos A Ordoñez; Mouaqit Ouadii; Andrew B Peitzman; Gennaro Perrone; Manos Pikoulis; Tadeja Pintar; Giuseppe Pipitone; Mauro Podda; Kemal Raşa; Julival Ribeiro; Gabriel Rodrigues; Ines Rubio-Perez; Ibrahima Sall; Norio Sato; Robert G Sawyer; Helmut Segovia Lohse; Gabriele Sganga; Vishal G Shelat; Ian Stephens; Michael Sugrue; Antonio Tarasconi; Joel Noutakdie Tochie; Matti Tolonen; Gia Tomadze; Jan Ulrych; Andras Vereczkei; Bruno Viaggi; Chiara Gurioli; Claudio Casella; Leonardo Pagani; Gian Luca Baiocchi; Fausto Catena
Journal:  World J Emerg Surg       Date:  2021-09-25       Impact factor: 5.469

3.  Metabolomic and inflammatory mediator based biomarker profiling as a potential novel method to aid pediatric appendicitis identification.

Authors:  Nusrat S Shommu; Craig N Jenne; Jaime Blackwood; Ari R Joffe; Dori-Ann Martin; Graham C Thompson; Hans J Vogel
Journal:  PLoS One       Date:  2018-03-12       Impact factor: 3.240

4.  Meta-analysis of peritoneal lavage in appendicectomy.

Authors:  E Gammeri; T Petrinic; G Bond-Smith; A Gordon-Weeks
Journal:  BJS Open       Date:  2018-11-29

5.  Intravenous versus intravenous/oral antibiotics for perforated appendicitis in pediatric patients: a systematic review and meta-analysis.

Authors:  Chuan Wang; Yanan Li; Yi Ji
Journal:  BMC Pediatr       Date:  2019-11-04       Impact factor: 2.125

Review 6.  Peritoneal irrigation vs suction alone during pediatric appendectomy for perforated appendicitis: A meta-analysis.

Authors:  Le-Wee Bi; Bei-Lei Yan; Qian-Yu Yang; Hua-Lei Cui
Journal:  Medicine (Baltimore)       Date:  2019-12       Impact factor: 1.817

7.  Diagnosis and management of acute appendicitis. EAES consensus development conference 2015.

Authors:  Ramon R Gorter; Hasan H Eker; Marguerite A W Gorter-Stam; Gabor S A Abis; Amish Acharya; Marjolein Ankersmit; Stavros A Antoniou; Simone Arolfo; Benjamin Babic; Luigi Boni; Marlieke Bruntink; Dieuwertje A van Dam; Barbara Defoort; Charlotte L Deijen; F Borja DeLacy; Peter Mnyh Go; Annelieke M K Harmsen; Rick S van den Helder; Florin Iordache; Johannes C F Ket; Filip E Muysoms; M Mahir Ozmen; Michail Papoulas; Michael Rhodes; Jennifer Straatman; Mark Tenhagen; Victor Turrado; Andras Vereczkei; Ramon Vilallonga; Jort D Deelder; Jaap Bonjer
Journal:  Surg Endosc       Date:  2016-09-22       Impact factor: 4.584

8.  Effectiveness of intraoperative peritoneal lavage (IOPL) with saline in patient with intra-abdominal infections: a systematic review and meta-analysis protocol.

Authors:  Qi Zhou; Qianling Shi; Xuan Yu; Zijun Wang; Jingyi Zhang; Nan Yang; Jianjian Wang; Yanfang Ma; Xufei Luo; Yangqin Xun; Siya Zhao; Bobo Zheng; Wenbo Meng; Kehu Yang; Yaolong Chen; Robert Sawyer
Journal:  BMJ Open       Date:  2020-07-19       Impact factor: 2.692

9.  Predictive factors of post-laparoscopic appendectomy peritoneal collection in children and adolescents with complicated appendicitis.

Authors:  Mohammad Gharieb Khirallah; Nagi Ebrahim Elsossuky; Mohamed Ghazaly
Journal:  Afr J Paediatr Surg       Date:  2021 Oct-Dec
  9 in total

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