Literature DB >> 22592942

Genetic and environmental causes of variation in perceived loneliness in young people.

Trine Waaktaar1, Svenn Torgersen.   

Abstract

Loneliness is prevalent in adolescence, despite the widespread expectation directed to young people to start building close relationships beyond the nuclear family. The aim of the present study was to explore the causal genetic and environmental structure behind variability in adolescents' perceived loneliness. Seven national cohorts (ages 12-18 years) of Norwegian twins reared together (1,394 twin pairs) participated. Perceived loneliness was measured with five items from the UCLA Loneliness Scale. Data were collected from mothers, fathers, and twins' self ratings by means of a posted questionnaire. Biometric analyses were applied, testing the causal architecture of loneliness within a psychometric model with one common latent factor in addition to specific genetic and environmental sources influencing the scores of each informant. The results showed a heritability (h(2)) of 75% on the latent perceived loneliness factor, and nonshared environmental effects (e(2)) explaining the remaining 25% of the latent factor variance. There were also significant rater-specific genetic and nonshared environmental effects. No shared environmental effects were found in the model, and there were no sex differences in the estimates. This study showed that variation in perceived loneliness in adolescents is highly genetic. Additional genetic and nonshared environmental etiological sources are to some extent represented in the scores of the specific rater.
Copyright © 2012 Wiley Periodicals, Inc.

Entities:  

Mesh:

Year:  2012        PMID: 22592942     DOI: 10.1002/ajmg.b.32064

Source DB:  PubMed          Journal:  Am J Med Genet B Neuropsychiatr Genet        ISSN: 1552-4841            Impact factor:   3.568


  5 in total

1.  Biological pathways and genetic mechanisms involved in social functioning.

Authors:  Juan R Ordoñana; Meike Bartels; Dorret I Boomsma; David Cella; Miriam Mosing; Joao R Oliveira; Donald L Patrick; Ruut Veenhoven; Gert G Wagner; Mirjam A G Sprangers
Journal:  Qual Life Res       Date:  2012-10-10       Impact factor: 4.147

2.  Genome-Wide Association Study of Loneliness Demonstrates a Role for Common Variation.

Authors:  Jianjun Gao; Lea K Davis; Amy B Hart; Sandra Sanchez-Roige; Lide Han; John T Cacioppo; Abraham A Palmer
Journal:  Neuropsychopharmacology       Date:  2016-09-15       Impact factor: 7.853

3.  Loneliness in Elderly People, Associated Factors and Its Correlation with Quality of Life: A Field Study from Western Turkey.

Authors:  Hülya Arslantaş; Filiz Adana; Filiz Abacigil Ergin; Derya Kayar; Gülçin Acar
Journal:  Iran J Public Health       Date:  2015-01       Impact factor: 1.429

4.  A SNP, Gene, and Polygenic Risk Score Approach of Oxytocin-Vasopressin Genes in Adolescents' Loneliness.

Authors:  Maaike Verhagen; Karin J H Verweij; Gerine M A Lodder; Luc Goossens; Karine Verschueren; Karla Van Leeuwen; Wim Van den Noortgate; Stephan Claes; Patricia Bijttebier; Evelien Van Assche; Jaqueline M Vink
Journal:  J Res Adolesc       Date:  2019-01-29

5.  The oxytocin receptor gene (OXTR) in relation to state levels of loneliness in adolescence: evidence for micro-level gene-environment interactions.

Authors:  Eeske van Roekel; Maaike Verhagen; Ron H J Scholte; Marloes Kleinjan; Luc Goossens; Rutger C M E Engels
Journal:  PLoS One       Date:  2013-11-04       Impact factor: 3.240

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.