Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Targeting endoglin, an auxiliary transforming growth factor β coreceptor, to prevent fibrosis and heart failure.

Literature DB >> 22592899

Targeting endoglin, an auxiliary transforming growth factor β coreceptor, to prevent fibrosis and heart failure.

Ivor J Benjamin.

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2012 PMID： 22592899 PMCID： PMC3401168 DOI： 10.1161/CIRCULATIONAHA.112.108282

Source DB: PubMed Journal: Circulation ISSN： 0009-7322 Impact factor: 29.690

× No keyword cloud information.

18 in total

1. Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure.

Authors: Navin K Kapur; Szuhuei Wilson; Adil A Yunis; Xiaoying Qiao; Emily Mackey; Vikram Paruchuri; Corey Baker; Mark J Aronovitz; S Ananth Karumanchi; Michelle Letarte; David A Kass; Michael E Mendelsohn; Richard H Karas
Journal: Circulation Date: 2012-05-16 Impact factor: 29.690

2. Endoglin negatively regulates transforming growth factor beta1-induced profibrotic responses in intestinal fibroblasts.

Authors: J P Burke; R W G Watson; J J Mulsow; N G Docherty; J C Coffey; P R O'Connell
Journal: Br J Surg Date: 2010-06 Impact factor: 6.939

3. Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure.

Authors: M R Bristow; R Ginsburg; V Umans; M Fowler; W Minobe; R Rasmussen; P Zera; R Menlove; P Shah; S Jamieson
Journal: Circ Res Date: 1986-09 Impact factor: 17.367

4. Treatment of chronic heart failure with β-adrenergic receptor antagonists: a convergence of receptor pharmacology and clinical cardiology.

Authors: Michael R Bristow
Journal: Circ Res Date: 2011-10-28 Impact factor: 17.367

5. Potential role of modifier genes influencing transforming growth factor-beta1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary hemorrhagic telangiectasia.

Authors: A Bourdeau; M E Faughnan; M L McDonald; A D Paterson; I R Wanless; M Letarte
Journal: Am J Pathol Date: 2001-06 Impact factor: 4.307

Review 6. The physiological role of endoglin in the cardiovascular system.

Authors: José M López-Novoa; Carmelo Bernabeu
Journal: Am J Physiol Heart Circ Physiol Date: 2010-07-23 Impact factor: 4.733

7. A murine model of hereditary hemorrhagic telangiectasia.

Authors: A Bourdeau; D J Dumont; M Letarte
Journal: J Clin Invest Date: 1999-11 Impact factor: 14.808

8. Atrial fibrosis helps select the appropriate patient and strategy in catheter ablation of atrial fibrillation: a DE-MRI guided approach.

Authors: Nazem Akoum; Marcos Daccarett; Chris McGann; Nathan Segerson; Gaston Vergara; Suman Kuppahally; Troy Badger; Nathan Burgon; Thomas Haslam; Eugene Kholmovski; Rob Macleod; Nassir Marrouche
Journal: J Cardiovasc Electrophysiol Date: 2010-08-30

9. Spontaneous adult-onset pulmonary arterial hypertension attributable to increased endothelial oxidative stress in a murine model of hereditary hemorrhagic telangiectasia.

Authors: Mourad Toporsian; Mirjana Jerkic; Yu-Qing Zhou; Mohammed G Kabir; Lisa X Yu; Brendan A S McIntyre; Adrienne Davis; Yu Jing Wang; Duncan J Stewart; Jaques Belik; Mansoor Husain; Mark Henkelman; Michelle Letarte
Journal: Arterioscler Thromb Vasc Biol Date: 2009-12-30 Impact factor: 8.311

10. Increased plasma soluble endoglin levels as an indicator of cardiovascular alterations in hypertensive and diabetic patients.

Authors: Ana M Blázquez-Medela; Luis García-Ortiz; Manuel A Gómez-Marcos; José I Recio-Rodríguez; Angel Sánchez-Rodríguez; José M López-Novoa; Carlos Martínez-Salgado
Journal: BMC Med Date: 2010-12-20 Impact factor: 8.775

5 in total

Targeting endoglin, an auxiliary transforming growth factor β coreceptor, to prevent fibrosis and heart failure.

1. Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure.

2. Endoglin negatively regulates transforming growth factor beta1-induced profibrotic responses in intestinal fibroblasts.

3. Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure.

4. Treatment of chronic heart failure with β-adrenergic receptor antagonists: a convergence of receptor pharmacology and clinical cardiology.

5. Potential role of modifier genes influencing transforming growth factor-beta1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary hemorrhagic telangiectasia.

Review 6. The physiological role of endoglin in the cardiovascular system.

7. A murine model of hereditary hemorrhagic telangiectasia.

8. Atrial fibrosis helps select the appropriate patient and strategy in catheter ablation of atrial fibrillation: a DE-MRI guided approach.

9. Spontaneous adult-onset pulmonary arterial hypertension attributable to increased endothelial oxidative stress in a murine model of hereditary hemorrhagic telangiectasia.

10. Increased plasma soluble endoglin levels as an indicator of cardiovascular alterations in hypertensive and diabetic patients.

1. Cells and pumps: Mechanical support and cellular therapy emerge as a realistic alternative to heart transplantation.

Review 2. The Role of Endoglin in Myocardial Fibrosis.

3. MicroRNA-208a increases myocardial fibrosis via endoglin in volume overloading heart.

4. Quantification of active and total transforming growth factor-β levels in serum and solid organ tissues by bioassay.

5. Oxidative stress, fibrosis, and early afterdepolarization-mediated cardiac arrhythmias.