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Literature DB >> 22592003

Nationwide surveillance study of human astrovirus infections in an Italian paediatric population.

S DE Grazia¹, V Martella², M Chironna³, F Bonura¹, F Tummolo⁴, A Calderaro⁴, P Moschidou², G M Giammanco¹, M C Medici⁴.

Abstract

The study investigated the genetic diversity of human astroviruses (HAstVs) detected in children hospitalized with gastroenteritis in Italy in 2008-2009. A total of 1321 faecal samples were collected in Parma (northern Italy), Bari (southern Italy), and Palermo (Sicily) and screened for the presence of HAstVs. RT-PCR amplification of a portion at the 5'-end of ORF2 allowed the detection of HAstVs in 3·95% of the patients. Four different genotypes (HAstV-1, HAstV-2, HAstV-4, HAstV-5) were found to be circulating during the study period, with HAstV-1 being the predominant type. Interestingly, a novel lineage, proposed as HAstV-2d, was found to have emerged in Parma in 2009. Investigating the genetic variability of HAstVs will be important for understanding the epidemiological trends and evolution of these viruses.

Entities: Chemical

Mesh：

Year: 2012 PMID： 22592003 PMCID： PMC9151877 DOI： 10.1017/S0950268812000945

Source DB: PubMed Journal: Epidemiol Infect ISSN： 0950-2688 Impact factor: 4.434

11 in total

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2. Wastewater Analysis Indicates that Genetically Diverse Astroviruses, Including Strains Belonging to Novel Clades MLB and VA, Are Circulating within Japanese Populations.

Authors: Akihiko Hata; Hiroyuki Katayama; Masaaki Kitajima; Hiroaki Furumai
Journal: Appl Environ Microbiol Date: 2015-05-15 Impact factor: 4.792

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