3-Benzyl-2H-chromen-2-one.

The title compound, C(16)H(12)O(2), is a coumarin which was isolated from stones of the Chinese traditional medicine Clausena lansium. The pyrone ring is almost planar, with a mean deviation of 0.0135 (4) Å. The benzene ring (A) of the benzopyrone unit forms dihedral angles of 1.82 (5) and 72.86 (2)° with the pyrone ring and the substituent benzene ring, respectively. The crystal structure is stabilized by weak π-π stacking inter-actions, with a minimum centroid-centroid distance between benzene rings of 3.6761 (7) Å.

Related literature

For general background to the isolation of the title compound, see: Wisanu et al. (2010 ▶, 2012 ▶). For the biological activity of Clausena lansium, see: Adebajo et al. (2009 ▶).

Experimental

Crystal data

C16H12O2

M = 236.26

Monoclinic,

a = 11.7704 (4) Å

b = 8.2809 (4) Å

c = 12.4652 (6) Å

β = 108.151 (2)°

V = 1154.52 (9) Å3

Z = 4

Mo Kα radiation

μ = 0.09 mm−1

T = 150 K

0.86 × 0.23 × 0.21 mm

Data collection

Bruker SMART CCD 1000 diffractometer

Absorption correction: multi-scan (SADABS; Sheldrick, 1996 ▶) T min = 0.928, T max = 0.982

8002 measured reflections

2475 independent reflections

2050 reflections with I > 2σ(I)

R int = 0.033

Refinement

R[F 2 > 2σ(F 2)] = 0.034

wR(F 2) = 0.093

S = 1.08

2475 reflections

163 parameters

H-atom parameters constrained

Δρmax = 0.24 e Å−3

Δρmin = −0.18 e Å−3

Data collection: SAINT (Bruker, 1998 ▶); cell refinement: SMART (Bruker, 1998 ▶); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008 ▶); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008 ▶); molecular graphics: OLEX2 (Dolomanov et al., 2009 ▶); software used to prepare material for publication: OLEX2.

Crystal structure: contains datablock(s) I, global. DOI: 10.1107/S1600536812014298/zs2199sup1.cif

Structure factors: contains datablock(s) I. DOI: 10.1107/S1600536812014298/zs2199Isup2.hkl

Supplementary material file. DOI: 10.1107/S1600536812014298/zs2199Isup3.cml

Additional supplementary materials: crystallographic information; 3D view; checkCIF report

C16H12O2	F(000) = 496
Mr = 236.26	Dx = 1.359 Mg m−3
Monoclinic, P21/c	Mo Kα radiation, λ = 0.710747 Å
a = 11.7704 (4) Å	Cell parameters from 8002 reflections
b = 8.2809 (4) Å	θ = 3–27.5°
c = 12.4652 (6) Å	µ = 0.09 mm−1
β = 108.151 (2)°	T = 150 K
V = 1154.52 (9) Å3	Prism, colourless
Z = 4	0.86 × 0.23 × 0.21 mm

Bruker SMART CCD 1000 diffractometer	2475 independent reflections
Radiation source: fine-focus sealed tube	2050 reflections with I > 2σ(I)
Graphite monochromator	Rint = 0.033
ω scans	θmax = 27.0°, θmin = 3.0°
Absorption correction: multi-scan (SADABS; Sheldrick, 1996)	h = −14→13
Tmin = 0.928, Tmax = 0.982	k = −10→10
8002 measured reflections	l = −12→15

Refinement on F2	Primary atom site location: structure-invariant direct methods
Least-squares matrix: full	Secondary atom site location: difference Fourier map
R[F2 > 2σ(F2)] = 0.034	Hydrogen site location: inferred from neighbouring sites
wR(F2) = 0.093	H-atom parameters constrained
S = 1.08	w = 1/[σ2(Fo2) + (0.0426P)2 + 0.2137P] where P = (Fo2 + 2Fc2)/3
2475 reflections	(Δ/σ)max < 0.001
163 parameters	Δρmax = 0.24 e Å−3
0 restraints	Δρmin = −0.18 e Å−3

Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell e.s.d.'s are taken into account individually in the estimation of e.s.d.'s in distances, angles and torsion angles; correlations between e.s.d.'s in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s. planes.

Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > σ(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger.

	x	y	z	Uiso*/Ueq
C1	0.38027 (9)	0.35804 (12)	0.36947 (9)	0.0229 (2)
C2	0.35856 (9)	0.38688 (11)	0.47770 (9)	0.0206 (2)
C3	0.43498 (9)	0.32578 (12)	0.57355 (9)	0.0213 (2)
H3	0.4219	0.3477	0.6436	0.026*
C4	0.53617 (9)	0.22788 (12)	0.57215 (9)	0.0206 (2)
C5	0.61806 (10)	0.16006 (13)	0.66886 (10)	0.0260 (3)
H5	0.6099	0.1803	0.7411	0.031*
C6	0.71066 (10)	0.06388 (13)	0.65934 (10)	0.0287 (3)
H6	0.7660	0.0191	0.7252	0.034*
C7	0.72314 (10)	0.03238 (12)	0.55376 (11)	0.0271 (3)
H7	0.7868	−0.0342	0.5482	0.033*
C8	0.64344 (9)	0.09730 (12)	0.45677 (10)	0.0251 (2)
H8	0.6511	0.0752	0.3846	0.030*
C9	0.55206 (9)	0.19552 (12)	0.46798 (9)	0.0206 (2)
C10	0.24760 (9)	0.48264 (12)	0.47378 (10)	0.0244 (2)
H10A	0.2366	0.5706	0.4177	0.029*
H10B	0.2586	0.5325	0.5485	0.029*
C11	0.13605 (9)	0.37716 (12)	0.44253 (9)	0.0216 (2)
C12	0.09172 (10)	0.31780 (13)	0.52614 (10)	0.0285 (3)
H12	0.1305	0.3453	0.6029	0.034*
C13	−0.00877 (11)	0.21854 (14)	0.49858 (11)	0.0323 (3)
H13	−0.0383	0.1794	0.5565	0.039*
C14	−0.06579 (10)	0.17677 (13)	0.38743 (11)	0.0296 (3)
H14	−0.1344	0.1092	0.3687	0.036*
C15	−0.02205 (10)	0.23422 (14)	0.30374 (11)	0.0307 (3)
H15	−0.0604	0.2051	0.2273	0.037*
C16	0.07789 (9)	0.33453 (13)	0.33096 (10)	0.0272 (3)
H16	0.1066	0.3742	0.2727	0.033*
O1	0.47592 (6)	0.26132 (9)	0.36983 (6)	0.02389 (19)
O2	0.32169 (7)	0.41253 (10)	0.27881 (7)	0.0331 (2)

	U11	U22	U33	U12	U13	U23
C1	0.0211 (5)	0.0238 (5)	0.0243 (6)	−0.0041 (4)	0.0078 (4)	0.0014 (4)
C2	0.0205 (5)	0.0186 (5)	0.0242 (6)	−0.0052 (4)	0.0092 (4)	−0.0015 (4)
C3	0.0233 (5)	0.0221 (5)	0.0209 (6)	−0.0049 (4)	0.0102 (4)	−0.0034 (4)
C4	0.0204 (5)	0.0199 (5)	0.0221 (6)	−0.0050 (4)	0.0076 (4)	−0.0012 (4)
C5	0.0273 (6)	0.0286 (5)	0.0217 (6)	−0.0024 (4)	0.0072 (4)	−0.0003 (4)
C6	0.0246 (6)	0.0268 (5)	0.0318 (7)	−0.0005 (4)	0.0045 (5)	0.0045 (5)
C7	0.0231 (5)	0.0199 (5)	0.0401 (7)	−0.0018 (4)	0.0126 (5)	−0.0016 (4)
C8	0.0262 (6)	0.0237 (5)	0.0294 (6)	−0.0053 (4)	0.0143 (5)	−0.0050 (4)
C9	0.0201 (5)	0.0199 (5)	0.0221 (6)	−0.0053 (4)	0.0071 (4)	−0.0006 (4)
C10	0.0238 (6)	0.0203 (5)	0.0292 (6)	−0.0012 (4)	0.0086 (4)	−0.0014 (4)
C11	0.0198 (5)	0.0179 (5)	0.0276 (6)	0.0031 (4)	0.0079 (4)	0.0001 (4)
C12	0.0312 (6)	0.0310 (6)	0.0254 (6)	−0.0042 (5)	0.0121 (5)	−0.0067 (5)
C13	0.0358 (6)	0.0343 (6)	0.0338 (7)	−0.0070 (5)	0.0207 (5)	−0.0034 (5)
C14	0.0224 (6)	0.0297 (6)	0.0372 (7)	−0.0056 (4)	0.0101 (5)	−0.0021 (5)
C15	0.0264 (6)	0.0368 (6)	0.0247 (6)	−0.0043 (5)	0.0020 (5)	0.0011 (5)
C16	0.0253 (6)	0.0307 (6)	0.0250 (6)	−0.0020 (4)	0.0067 (4)	0.0066 (4)
O1	0.0247 (4)	0.0297 (4)	0.0191 (4)	−0.0007 (3)	0.0094 (3)	0.0003 (3)
O2	0.0314 (4)	0.0432 (5)	0.0240 (5)	0.0019 (4)	0.0077 (3)	0.0089 (4)

C1—C2	1.4687 (15)	C8—C9	1.3898 (15)
C1—O1	1.3805 (13)	C9—O1	1.3834 (13)
C1—O2	1.2128 (13)	C10—H10A	0.9900
C2—C3	1.3502 (15)	C10—H10B	0.9900
C2—C10	1.5157 (14)	C10—C11	1.5231 (14)
C3—H3	0.9500	C11—C12	1.3925 (15)
C3—C4	1.4453 (14)	C11—C16	1.3908 (16)
C4—C5	1.4050 (15)	C12—H12	0.9500
C4—C9	1.3944 (16)	C12—C13	1.3927 (16)
C5—H5	0.9500	C13—H13	0.9500
C5—C6	1.3845 (16)	C13—C14	1.3821 (18)
C6—H6	0.9500	C14—H14	0.9500
C6—C7	1.3937 (17)	C14—C15	1.3836 (17)
C7—H7	0.9500	C15—H15	0.9500
C7—C8	1.3871 (16)	C15—C16	1.3930 (15)
C8—H8	0.9500	C16—H16	0.9500
O1—C1—C2	117.80 (9)	O1—C9—C8	116.75 (10)
O2—C1—C2	125.76 (10)	C2—C10—H10A	109.2
O2—C1—O1	116.43 (10)	C2—C10—H10B	109.2
C1—C2—C10	116.75 (9)	C2—C10—C11	111.95 (8)
C3—C2—C1	119.56 (9)	H10A—C10—H10B	107.9
C3—C2—C10	123.67 (10)	C11—C10—H10A	109.2
C2—C3—H3	119.2	C11—C10—H10B	109.2
C2—C3—C4	121.59 (10)	C12—C11—C10	120.34 (10)
C4—C3—H3	119.2	C16—C11—C10	121.18 (10)
C5—C4—C3	124.16 (10)	C16—C11—C12	118.46 (10)
C9—C4—C3	117.98 (10)	C11—C12—H12	119.6
C9—C4—C5	117.84 (10)	C11—C12—C13	120.74 (11)
C4—C5—H5	119.9	C13—C12—H12	119.6
C6—C5—C4	120.29 (11)	C12—C13—H13	119.8
C6—C5—H5	119.9	C14—C13—C12	120.33 (11)
C5—C6—H6	119.8	C14—C13—H13	119.8
C5—C6—C7	120.40 (11)	C13—C14—H14	120.3
C7—C6—H6	119.8	C13—C14—C15	119.42 (11)
C6—C7—H7	119.7	C15—C14—H14	120.3
C8—C7—C6	120.58 (10)	C14—C15—H15	119.8
C8—C7—H7	119.7	C14—C15—C16	120.38 (11)
C7—C8—H8	120.9	C16—C15—H15	119.8
C7—C8—C9	118.28 (11)	C11—C16—C15	120.67 (11)
C9—C8—H8	120.9	C11—C16—H16	119.7
C8—C9—C4	122.59 (10)	C15—C16—H16	119.7
O1—C9—C4	120.66 (9)	C1—O1—C9	122.30 (9)
C1—C2—C3—C4	−1.97 (14)	C7—C8—C9—O1	178.51 (9)
C1—C2—C10—C11	82.11 (11)	C8—C9—O1—C1	178.61 (9)
C2—C1—O1—C9	−1.63 (13)	C9—C4—C5—C6	−0.30 (15)
C2—C3—C4—C5	−179.48 (9)	C10—C2—C3—C4	176.63 (9)
C2—C3—C4—C9	−1.02 (14)	C10—C11—C12—C13	−178.67 (10)
C2—C10—C11—C12	98.80 (12)	C10—C11—C16—C15	178.15 (10)
C2—C10—C11—C16	−79.60 (12)	C11—C12—C13—C14	0.32 (18)
C3—C2—C10—C11	−96.53 (12)	C12—C11—C16—C15	−0.27 (16)
C3—C4—C5—C6	178.17 (9)	C12—C13—C14—C15	0.10 (18)
C3—C4—C9—C8	−177.27 (9)	C13—C14—C15—C16	−0.60 (18)
C3—C4—C9—O1	2.74 (14)	C14—C15—C16—C11	0.70 (17)
C4—C5—C6—C7	−0.46 (16)	C16—C11—C12—C13	−0.23 (16)
C4—C9—O1—C1	−1.39 (14)	O1—C1—C2—C3	3.29 (14)
C5—C4—C9—C8	1.30 (15)	O1—C1—C2—C10	−175.41 (8)
C5—C4—C9—O1	−178.70 (8)	O2—C1—C2—C3	−176.32 (10)
C5—C6—C7—C8	0.27 (16)	O2—C1—C2—C10	4.98 (15)
C6—C7—C8—C9	0.68 (15)	O2—C1—O1—C9	178.02 (9)
C7—C8—C9—C4	−1.49 (15)