Literature DB >> 22589656

Theophylline toxicity: A case report of the survival of an undiagnosed patient who presented to the emergency department.

Nasir Mohamad1, Nurkhairul Nizam Abd Halim, Rashidi Ahmad, Kamarul Aryffin Baharuddin.   

Abstract

Theophylline toxicity is a life-threatening toxidrome that can present to an emergency department. To ascertain an immediate provisional diagnosis in toxicology at the emergency department is very challenging, especially when the patient presents with altered mental status, because the clinical features of several toxidromes overlap. We report a case of survival of undiagnosed theophylline toxicity that required intubation for two days in the intensive care unit. This was the first case to have been reported from our department. Accurate diagnosis of a toxidrome by gaining adequate history and conducting a thorough physical examination and early serum toxicology screening, coupled with good knowledge of toxicology, will lead to better patient outcomes.

Entities:  

Keywords:  Theophylline; emergency medicine; medical sciences; toxicity

Year:  2009        PMID: 22589656      PMCID: PMC3336170     

Source DB:  PubMed          Journal:  Malays J Med Sci        ISSN: 1394-195X


  20 in total

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Authors:  M F Bonfiglio; J F Dasta
Journal:  Pharmacotherapy       Date:  1991       Impact factor: 4.705

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Journal:  Am J Emerg Med       Date:  1996-10       Impact factor: 2.469

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Journal:  Am Fam Physician       Date:  1996-10       Impact factor: 3.292

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Journal:  Pharmacotherapy       Date:  1990       Impact factor: 4.705

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Journal:  Pediatrics       Date:  1987-09       Impact factor: 7.124

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Journal:  Clin Pharmacol Ther       Date:  1983-11       Impact factor: 6.875

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Journal:  Am J Emerg Med       Date:  1985-09       Impact factor: 2.469

8.  Pronounced metabolic response to modest theophylline overdose.

Authors:  M T Hagley; S M Traeger; H Schuckman
Journal:  Ann Pharmacother       Date:  1994-02       Impact factor: 3.154

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Authors:  M Shannon
Journal:  Ann Intern Med       Date:  1993-12-15       Impact factor: 25.391

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Authors:  S Sahney; J Abarzua; L Sessums
Journal:  Pediatrics       Date:  1983-04       Impact factor: 7.124

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  1 in total

1.  Case Report: The risks associated with chronic theophylline therapy and measures designed to improve monitoring and management.

Authors:  Michael E Hopkins; Robert V MacKenzie-Ross
Journal:  BMC Pharmacol Toxicol       Date:  2016-03-05       Impact factor: 2.483

  1 in total

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