Literature DB >> 22588807

Depleted Uranium. Is it potentially involved in the recent upsurge of malignancies in populations exposed to war dust?

Hamdi H Shelleh1.   

Abstract

Due to its extreme density, depleted Uranium (DU) has recently entered the warfare industry and became a major pollutant to the biosphere. Although DU is less radioactive than natural Uranium, it still retains all its chemical toxicity. Limited data exists regarding the long-term hazards of DU on humans, however, it is suspected to be a major toxic and mutagenic agent. Literature review reveals the scarcity of the World Health Organization's knowledge regarding related DU-malignancies. Battlefield reports documented a steady rise of malignancies and newborn malformations after war, that is, leukemia in the Balkans, and congenital anomalies and Kaposi sarcoma (KS) in Iraq. Kaposi sarcoma in Iraq has a quite aggressive behavior compared with the classic KS before, suggesting a potential relation with DU, and possibly a different DU related KS-type. Children are more susceptible to radiation than adults. This enlarges the responsibility of the medical communities for an evidence-based attitude towards DU, and to ban its use until proven otherwise. We, as medical bodies have a human approach - stand with man not to be mistreated, and with green norms, which veto all suspected pollutants of the planet. Until further notice, DU should be thoroughly checked for safety, before it kills.

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Year:  2012        PMID: 22588807

Source DB:  PubMed          Journal:  Saudi Med J        ISSN: 0379-5284            Impact factor:   1.484


  5 in total

Review 1.  Medical effects of internal contamination with actinides: further controversy on depleted uranium and radioactive warfare.

Authors:  Asaf Durakovic
Journal:  Environ Health Prev Med       Date:  2016-03-22       Impact factor: 3.674

2.  Analysis of heat-labile sites generated by reactions of depleted uranium and ascorbate in plasmid DNA.

Authors:  Janice Wilson; Ashley Young; Edgar R Civitello; Diane M Stearns
Journal:  J Biol Inorg Chem       Date:  2013-11-12       Impact factor: 3.358

3.  Synergistic cytotoxicity and DNA strand breaks in cells and plasmid DNA exposed to uranyl acetate and ultraviolet radiation.

Authors:  Janice Wilson; Mary C Zuniga; Filbert Yazzie; Diane M Stearns
Journal:  J Appl Toxicol       Date:  2014-05-15       Impact factor: 3.446

4.  Incidence of haematological malignancies in Kosovo-A post "uranium war" concern.

Authors:  Hatixhe Latifi-Pupovci; Miranda Selmonaj; Blerina Ahmetaj-Shala; Mimoza Dushi; Violeta Grajqevci
Journal:  PLoS One       Date:  2020-05-04       Impact factor: 3.240

Review 5.  Rapidly progressive Kaposi's Sarcoma in an Iraqi boy received Valproic acid: a case report and review of literature.

Authors:  Lika'a Fasih Y Al-Kzayer; Peter Keizer; Farah T Abdulraheem; Kenji Sano; Minoru Kamata; Kazuo Sakashita; Laith A Y Habbaba; Kenichi Koike
Journal:  BMC Pediatr       Date:  2016-07-26       Impact factor: 2.125

  5 in total

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