Literature DB >> 22587819

Risk of catheter-associated infection in young hematology/oncology patients receiving long-term peripheral nerve blocks.

Doralina L Anghelescu1, Brittney L Harris, Lane G Faughnan, Linda L Oakes, Kelley B Windsor, Becky B Wright, Jonathan A McCullers.   

Abstract

BACKGROUND: Continuous peripheral nerve blocks (CPNBs) are increasingly used to control postoperative and chronic pain. At our pediatric oncology institution, the duration of CPNBs is often prolonged. The risk of catheter-associated infection with prolonged CPNBs has not been previously investigated. AIM: We analyzed the incidence of CPNB-related infection and its relation to catheter duration, catheter site, intensive care stay, and antibiotic coverage.
METHODS: All CPNBs placed at our institution between August 1, 2005 and October 31, 2010 were studied. Primary diagnosis and the site, indication, duration, and infectious adverse effects of CPNBs were obtained from our Pain Service QI database. Patients' age and sex, antibiotic administration, and number of days in intensive care were collected from patients' medical records.
RESULTS: The use of 179 catheters in 116 patients was evaluated. Mean age at CPNB placement was 15.1 years (median, 14.7; range, 0.4-26.9). The most frequent indication for CPNB was surgery (89.4%), most commonly orthopedic (78.8%). Mean CPNB duration was 7.2 days (median, 5.0; range, 1-81 days). Two cases (1.12%) of CPNBs developed signs of infection, both associated with femoral catheters. The infections were mild and necessitated catheter removal at days 10 and 13, respectively.
CONCLUSION: Nerve block catheter-associated infections are infrequent at our institution despite prolonged CPNB use. Both patients with infection had femoral catheters and prolonged catheter (≥ 10 days) use.
© 2012 Blackwell Publishing Ltd.

Entities:  

Keywords:  infection; oncology; pain; peripheral nerve block

Mesh:

Substances:

Year:  2012        PMID: 22587819      PMCID: PMC3422424          DOI: 10.1111/j.1460-9592.2012.03880.x

Source DB:  PubMed          Journal:  Paediatr Anaesth        ISSN: 1155-5645            Impact factor:   2.556


  13 in total

Review 1.  Infectious risk of continuous peripheral nerve blocks.

Authors:  Xavier Capdevila; Sophie Bringuier; Alain Borgeat
Journal:  Anesthesiology       Date:  2009-01       Impact factor: 7.892

2.  Acute neck cellulitis and mediastinitis complicating a continuous interscalene block.

Authors:  Xavier Capdevila; Samir Jaber; Pertti Pesonen; Alain Borgeat; Jean-Jacques Eledjam
Journal:  Anesth Analg       Date:  2008-10       Impact factor: 5.108

3.  Use of epidural and peripheral nerve blocks at the end of life in children and young adults with cancer: the collaboration between a pain service and a palliative care service.

Authors:  Doralina L Anghelescu; Lane G Faughnan; Justin N Baker; Jie Yang; Javier R Kane
Journal:  Paediatr Anaesth       Date:  2010-12       Impact factor: 2.556

4.  Continuous peripheral nerve blocks in hospital wards after orthopedic surgery: a multicenter prospective analysis of the quality of postoperative analgesia and complications in 1,416 patients.

Authors:  Xavier Capdevila; Philippe Pirat; Sophie Bringuier; Elisabeth Gaertner; François Singelyn; Nathalie Bernard; Olivier Choquet; Hervé Bouaziz; Francis Bonnet
Journal:  Anesthesiology       Date:  2005-11       Impact factor: 7.892

5.  The continuous femoral nerve block catheter for postoperative analgesia: bacterial colonization, infectious rate and adverse effects.

Authors:  P Cuvillon; J Ripart; L Lalourcey; E Veyrat; J L'Hermite; C Boisson; E Thouabtia; J J Eledjam
Journal:  Anesth Analg       Date:  2001-10       Impact factor: 5.108

Review 6.  Continuous peripheral nerve blocks in acute pain management.

Authors:  J E Chelly; D Ghisi; A Fanelli
Journal:  Br J Anaesth       Date:  2010-12       Impact factor: 9.166

7.  Clinical signs of infection during continuous postoperative epidural analgesia in children: the value of catheter tip culture.

Authors:  N Seth; S Macqueen; R F Howard
Journal:  Paediatr Anaesth       Date:  2004-12       Impact factor: 2.556

8.  Bacterial colonization and infection rate of continuous epidural catheters in children.

Authors:  S Kost-Byerly; J R Tobin; R S Greenberg; C Billett; M Zahurak; M Yaster
Journal:  Anesth Analg       Date:  1998-04       Impact factor: 5.108

9.  Continuous peripheral nerve blockade for inpatient and outpatient postoperative analgesia in children.

Authors:  Arjunan Ganesh; John B Rose; Lawrence Wells; Theodore Ganley; Harshad Gurnaney; Lynne G Maxwell; Theresa DiMaggio; Karen Milovcich; Maureen Scollon; Jeffrey M Feldman; Giovanni Cucchiaro
Journal:  Anesth Analg       Date:  2007-11       Impact factor: 5.108

10.  Risk factors for bacterial catheter colonization in regional anaesthesia.

Authors:  Astrid M Morin; Klaus M Kerwat; Martina Klotz; Roswitha Niestolik; Veronika E Ruf; Hinnerk Wulf; Stefan Zimmermann; Leopold Hj Eberhart
Journal:  BMC Anesthesiol       Date:  2005-03-17       Impact factor: 2.217

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  1 in total

1.  Regional anesthesia for an upper extremity amputation for palliative care in a patient with end-stage osteosarcoma complicated by a large anterior mediastinal mass.

Authors:  Mumin Hakim; Candice Burrier; Tarun Bhalla; Vidya T Raman; David P Martin; Olamide Dairo; Joel L Mayerson; Joseph D Tobias
Journal:  J Pain Res       Date:  2015-09-24       Impact factor: 3.133

  1 in total

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