Literature DB >> 22586352

New routes to old places: PIK3R1 and PIK3R2 join PIK3CA and PTEN as endometrial cancer genes.

Sandra Herrero-Gonzalez1, Antonio Di Cristofano.   

Abstract

Cheung and colleagues identify PIK3R1 and PIK3R2, the genes encoding the α and β isoforms of the phosphatidylinositol 3-kinase (PI3K) p85 regulatory subunit, as additional mutation targets in endometrial cancer, and describe a novel mechanism leading to PTEN loss.

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Year:  2011        PMID： 22586352     DOI： 10.1158/2159-8290.CD-11-0116

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  5 in total

1.  Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer.

Authors:  Iris N Smith; James M Briggs
Journal:  Proteins       Date:  2016-08-13

2.  Identification of genes and pathways potentially related to PHF20 by gene expression profile analysis of glioblastoma U87 cell line.

Authors:  Tianlong Liu; Tiejun Zhang; Feng Zhou; Jitao Wang; Xiaohu Zhai; Nan Mu; Jongsun Park; Minna Liu; Wenxing Liu; Peijin Shang; Yi Ding; Aidong Wen; Yuwen Li
Journal:  Cancer Cell Int       Date:  2017-10-04       Impact factor: 5.722

3.  Network propagation-based prioritization of long tail genes in 17 cancer types.

Authors:  Hussein Mohsen; Vignesh Gunasekharan; Tao Qing; Montrell Seay; Yulia Surovtseva; Sahand Negahban; Zoltan Szallasi; Lajos Pusztai; Mark B Gerstein
Journal:  Genome Biol       Date:  2021-10-07       Impact factor: 13.583

4.  miR-126-3p Inhibits Thyroid Cancer Cell Growth and Metastasis, and Is Associated with Aggressive Thyroid Cancer.

Authors:  Yin Xiong; Shweta Kotian; Martha A Zeiger; Lisa Zhang; Electron Kebebew
Journal:  PLoS One       Date:  2015-08-05       Impact factor: 3.240

5.  Single-walled and multi-walled carbon nanotubes induce sequence-specific epigenetic alterations in 16 HBE cells.

Authors:  Manosij Ghosh; Deniz Öner; Radu C Duca; Bram Bekaert; Jeroen A J Vanoirbeek; Lode Godderis; Peter H M Hoet
Journal:  Oncotarget       Date:  2018-04-17
  5 in total

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