Literature DB >> 2258593

[The Hellp syndrome: is this a clinical form of thrombotic microangiopathy?].

B Ducroz1, P Villemonteix, G Magnin, O Pourrat.   

Abstract

There are similarities between the clinical, biological and histological features of thrombotic micro-angiopathy (TMA) when it is a complication of pregnancy and the "Help Syndrome" (HS). HS can be associated in pregnancy with pre-eclampsia, thrombocytopenia, micro-angiopathic haemolysis and hepatic cytolysis. We have analysed on the one hand biological features of six cases that occurred in the literature and two personal cases of thrombotic micro-angiopathy that had been proven histologically; and on the other hand the histological findings of the liver in two cases of the literature and in a personal case of HS. Demonstration that in HS deposits exist under the endothelium in the region of the hepatic biopsy suggest that the latter can only be a special clinical form of TMA.

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Year:  1990        PMID: 2258593

Source DB:  PubMed          Journal:  J Gynecol Obstet Biol Reprod (Paris)        ISSN: 0150-9918


  2 in total

Review 1.  HELLP syndrome as a cause of unexpected rapid maternal death--a case report and review of the literature.

Authors:  M Simic; M Tasic; G Stojiljkovic; D Draskovic; R Vukovic
Journal:  Int J Legal Med       Date:  2004-11-11       Impact factor: 2.686

Review 2.  Renal involvement in preeclampsia: similarities to VEGF ablation therapy.

Authors:  Janina Müller-Deile; Mario Schiffer
Journal:  J Pregnancy       Date:  2010-12-23
  2 in total

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