Literature DB >> 22585704

Targeting the Notch pathway: twists and turns on the road to rational therapeutics.

Jon C Aster1, Stephen C Blacklow.   

Abstract

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Year:  2012        PMID： 22585704     DOI： 10.1200/JCO.2012.42.0992

Source DB:  PubMed          Journal:  J Clin Oncol        ISSN： 0732-183X            Impact factor:   44.544


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  39 in total

1.  Bromodomain and hedgehog pathway targets in small cell lung cancer.

Authors:  Gurmeet Kaur; Russell A Reinhart; Anne Monks; David Evans; Joel Morris; Eric Polley; Beverly A Teicher
Journal:  Cancer Lett       Date:  2015-12-10       Impact factor: 8.679

2.  Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features.

Authors:  Eleni M Rettig; Christine H Chung; Justin A Bishop; Jason D Howard; Rajni Sharma; Ryan J Li; Christopher Douville; Rachel Karchin; Evgeny Izumchenko; David Sidransky; Wayne Koch; Joseph Califano; Nishant Agrawal; Carole Fakhry
Journal:  Cancer Prev Res (Phila)       Date:  2015-01-29

3.  Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia.

Authors:  Monique Dail; Jason Wong; Jessica Lawrence; Daniel O'Connor; Joy Nakitandwe; Shann-Ching Chen; Jin Xu; Leslie B Lee; Keiko Akagi; Qing Li; Jon C Aster; Warren S Pear; James R Downing; Deepak Sampath; Kevin Shannon
Journal:  Nature       Date:  2014-07-20       Impact factor: 49.962

4.  Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma.

Authors:  Alexander Stoeck; Serguei Lejnine; Andrew Truong; Li Pan; Hongfang Wang; Chongzhi Zang; Jing Yuan; Chris Ware; John MacLean; Philip W Garrett-Engele; Michael Kluk; Jason Laskey; Brian B Haines; Christopher Moskaluk; Leigh Zawel; Stephen Fawell; Gary Gilliland; Theresa Zhang; Brandon E Kremer; Birgit Knoechel; Bradley E Bernstein; Warren S Pear; X Shirley Liu; Jon C Aster; Sriram Sathyanarayanan
Journal:  Cancer Discov       Date:  2014-08-07       Impact factor: 39.397

Review 5.  Targeting the Angiopoietin-2/Tie-2 axis in conjunction with VEGF signal interference.

Authors:  Nikolett M Biel; Dietmar W Siemann
Journal:  Cancer Lett       Date:  2014-10-12       Impact factor: 8.679

6.  γ-Secretase Inhibition Lowers Plasma Triglyceride-Rich Lipoproteins by Stabilizing the LDL Receptor.

Authors:  KyeongJin Kim; Ira J Goldberg; Mark J Graham; Meenakshi Sundaram; Enrico Bertaggia; Samuel X Lee; Li Qiang; Rebecca A Haeusler; Daniel Metzger; Pierre Chambon; Zemin Yao; Henry N Ginsberg; Utpal B Pajvani
Journal:  Cell Metab       Date:  2018-03-22       Impact factor: 27.287

Review 7.  Targeting notch signaling pathway in cancer: clinical development advances and challenges.

Authors:  Naoko Takebe; Dat Nguyen; Sherry X Yang
Journal:  Pharmacol Ther       Date:  2013-09-27       Impact factor: 12.310

8.  Discovery of a ZIP7 inhibitor from a Notch pathway screen.

Authors:  Erin Nolin; Sara Gans; Luis Llamas; Somnath Bandyopadhyay; Scott M Brittain; Paula Bernasconi-Elias; Kyle P Carter; Joseph J Loureiro; Jason R Thomas; Markus Schirle; Yi Yang; Ning Guo; Guglielmo Roma; Sven Schuierer; Martin Beibel; Alicia Lindeman; Frederic Sigoillot; Amy Chen; Kevin X Xie; Samuel Ho; John Reece-Hoyes; Wilhelm A Weihofen; Kayla Tyskiewicz; Dominic Hoepfner; Richard I McDonald; Nicolette Guthrie; Abhishek Dogra; Haibing Guo; Jian Shao; Jian Ding; Stephen M Canham; Geoff Boynton; Elizabeth L George; Zhao B Kang; Christophe Antczak; Jeffery A Porter; Owen Wallace; John A Tallarico; Amy E Palmer; Jeremy L Jenkins; Rishi K Jain; Simon M Bushell; Christy J Fryer
Journal:  Nat Chem Biol       Date:  2019-01-14       Impact factor: 15.040

9.  Functional redundancy of the Notch pathway in ovarian cancer cell lines.

Authors:  Fernanda Silva; Ana Félix; Jacinta Serpa
Journal:  Oncol Lett       Date:  2016-08-05       Impact factor: 2.967

10.  Structure and function of the CSL-KyoT2 corepressor complex: a negative regulator of Notch signaling.

Authors:  Kelly J Collins; Zhenyu Yuan; Rhett A Kovall
Journal:  Structure       Date:  2013-11-27       Impact factor: 5.006
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