| Literature DB >> 22585165 |
Christopher L Corless1, Paul T Spellman.
Abstract
Most tumor samples available for clinical genotyping are formalin-fixed and paraffin-embedded (FFPE), but there has been relatively little published on the suitability of such samples for next-generation sequencing approaches. A new study by Wagle and colleagues shows that a combination of hybridization-capture and deep sequencing yields high-quality data from FFPE specimens.Entities:
Mesh:
Year: 2012 PMID: 22585165 DOI: 10.1158/2159-8290.CD-11-0319
Source DB: PubMed Journal: Cancer Discov ISSN: 2159-8274 Impact factor: 39.397