| Literature DB >> 22585164 |
Nancy E Hynes1, Tatiana Smirnova.
Abstract
Ling and colleagues demonstrated that loss of the conditional 14-3-3σ allele results in accelerated HER2/ERBB2-driven mammary tumorigenesis and metastasis. This study underscores the role of 14-3-3σ as a potent tumor suppressor in ERBB2-driven tumor initiation and progression.Entities:
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Year: 2012 PMID： 22585164 DOI： 10.1158/2159-8290.CD-11-0317
Source DB: PubMed Journal: Cancer Discov ISSN： 2159-8274 Impact factor: 39.397