Literature DB >> 22583112

Asymmetric pericyclic cascade approach to spirocyclic oxindoles.

Edward Richmond1, Nicolas Duguet, Alexandra M Z Slawin, Tomáš Lébl, Andrew D Smith.   

Abstract

The reaction of chiral N-arylnitrones with carbocyclic alkylarylketenes generates spirocyclic oxindoles in good yields and with excellent levels of enantioselectivity (90-99% ee) via a pericyclic cascade process.

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Year:  2012        PMID： 22583112     DOI： 10.1021/ol300982f

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  dM-Dim for Carboxylic Acid Protection.

Authors:  Shahien Shahsavari; Travis Wigstrom; James Gooding; Chase McNamara; Shiyue Fang
Journal:  Tetrahedron Lett       Date:  2018-03-27       Impact factor: 2.415

2.  Visible-light-promoted nitrone synthesis from nitrosoarenes under catalyst- and additive-free conditions.

Authors:  Bao-Gui Cai; Lin Li; Guo-Yong Xu; Wen-Jing Xiao; Jun Xuan
Journal:  Photochem Photobiol Sci       Date:  2021-06-11       Impact factor: 3.982

Review 3.  Molecular diversity of spirooxindoles. Synthesis and biological activity.

Authors:  Tetyana L Pavlovska; Ruslan Gr Redkin; Victoria V Lipson; Dmytro V Atamanuk
Journal:  Mol Divers       Date:  2015-09-29       Impact factor: 2.943

4.  Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.

Authors:  Katherine M Byrd; Chitra Subramanian; Jacqueline Sanchez; Hashim F Motiwala; Weiya Liu; Mark S Cohen; Jeffrey Holzbeierlein; Brian S J Blagg
Journal:  Chemistry       Date:  2016-04-01       Impact factor: 5.236

5.  Stereoselective syntheses of functionalized spirocyclopenteneoxindoles via triphenylphosphine-catalyzed [3+2] cycloaddition reactions.

Authors:  Qing-Fa Zhou; Xue-Ping Chu; Fei-Fei Ge; Cheng Li; Tao Lu
Journal:  Mol Divers       Date:  2013-06-19       Impact factor: 2.943
  5 in total

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