Literature DB >> 22581934

NLRs, inflammasomes, and viral infection.

Sarah R Jacobs1, Blossom Damania.   

Abstract

NLR proteins are innate immune sensors that respond to microbial infection. Upon pathogen infection, some NLR proteins form large complexes, called inflammasomes, which activate caspase-1 and induce the production of active IL-1β and IL-18. Activation of inflammasomes can also lead to an inflammatory cell death program, named pyroptosis. In this review, we will discuss the role of various NLR proteins in sensing different viral infections, as well as the strategies used by several RNA and DNA viruses to counteract the antiviral effects of NLR-dependent inflammasomes.

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Year:  2012        PMID： 22581934      PMCID： PMC4046246          DOI： 10.1189/jlb.0312132

Source DB:  PubMed          Journal:  J Leukoc Biol        ISSN： 0741-5400            Impact factor:   4.962


  123 in total

1.  Inflammasome-mediated regulation of hepatic stellate cells.

Authors:  Azuma Watanabe; Muhammad Adnan Sohail; Dawidson Assis Gomes; Ardeshir Hashmi; Jun Nagata; Fayyaz Shiraz Sutterwala; Shamail Mahmood; Muhammad Nauman Jhandier; Yan Shi; Richard Anthony Flavell; Wajahat Zafar Mehal
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2009-04-09       Impact factor: 4.052

2.  An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix.

Authors:  Damien Arnoult; Fraser Soares; Ivan Tattoli; Céline Castanier; Dana J Philpott; Stephen E Girardin
Journal:  J Cell Sci       Date:  2009-09-01       Impact factor: 5.285

3.  Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo.

Authors:  Nelson C Di Paolo; Edward A Miao; Yoichiro Iwakura; Kaja Murali-Krishna; Alan Aderem; Richard A Flavell; Thalia Papayannopoulou; Dmitry M Shayakhmetov
Journal:  Immunity       Date:  2009-07-02       Impact factor: 31.745

4.  Negative regulation of MAVS-mediated innate immune response by PSMA7.

Authors:  Yongxia Jia; Ting Song; Congwen Wei; Caifei Ni; Zirui Zheng; Quanbin Xu; Hongfang Ma; Li Li; Yanhong Zhang; Xiang He; Yang Xu; Wei Shi; Hui Zhong
Journal:  J Immunol       Date:  2009-09-04       Impact factor: 5.422

5.  Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages.

Authors:  Adel M Nour; Yee-Guide Yeung; Laura Santambrogio; Eric D Boyden; E Richard Stanley; Jürgen Brojatsch
Journal:  Infect Immun       Date:  2009-01-05       Impact factor: 3.441

6.  The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.

Authors:  Irving C Allen; Margaret A Scull; Chris B Moore; Eda K Holl; Erin McElvania-TeKippe; Debra J Taxman; Elizabeth H Guthrie; Raymond J Pickles; Jenny P-Y Ting
Journal:  Immunity       Date:  2009-04-09       Impact factor: 31.745

7.  NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury.

Authors:  Kenshi Yamasaki; Jun Muto; Kristen R Taylor; Anna L Cogen; David Audish; John Bertin; Ethan P Grant; Anthony J Coyle; Amirhossein Misaghi; Hal M Hoffman; Richard L Gallo
Journal:  J Biol Chem       Date:  2009-03-03       Impact factor: 5.157

8.  Activation of innate immune antiviral responses by Nod2.

Authors:  Ahmed Sabbah; Te Hung Chang; Rosalinda Harnack; Victoria Frohlich; Kaoru Tominaga; Peter H Dube; Yan Xiang; Santanu Bose
Journal:  Nat Immunol       Date:  2009-08-23       Impact factor: 25.606

9.  Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity.

Authors:  Amy S McKee; Michael W Munks; Megan K L MacLeod; Courtney J Fleenor; Nico Van Rooijen; John W Kappler; Philippa Marrack
Journal:  J Immunol       Date:  2009-09-04       Impact factor: 5.422

10.  Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome.

Authors:  Julie Delaloye; Thierry Roger; Quynh-Giao Steiner-Tardivel; Didier Le Roy; Marlies Knaup Reymond; Shizuo Akira; Virginie Petrilli; Carmen E Gomez; Beatriz Perdiguero; Jürg Tschopp; Giuseppe Pantaleo; Mariano Esteban; Thierry Calandra
Journal:  PLoS Pathog       Date:  2009-06-19       Impact factor: 6.823
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  26 in total

Review 1.  New insights into TRP channels: Interaction with pattern recognition receptors.

Authors:  Huirong Han; Fan Yi
Journal:  Channels (Austin)       Date:  2013-12-03       Impact factor: 2.581

Review 2.  Innate Sensing of DNA Virus Genomes.

Authors:  Zhe Ma; Guoxin Ni; Blossom Damania
Journal:  Annu Rev Virol       Date:  2018-09-29       Impact factor: 10.431

Review 3.  Kaposi sarcoma-associated herpesvirus: immunobiology, oncogenesis, and therapy.

Authors:  Dirk P Dittmer; Blossom Damania
Journal:  J Clin Invest       Date:  2016-09-01       Impact factor: 14.808

4.  Chemical cross-linking of HIV-1 Env for direct TLR7/8 ligand conjugation compromises recognition of conserved antigenic determinants.

Authors:  Yu Feng; Mattias N E Forsell; Barbara Flynn; William Adams; Karin Loré; Robert Seder; Richard T Wyatt; Gunilla B Karlsson Hedestam
Journal:  Virology       Date:  2013-08-15       Impact factor: 3.616

Review 5.  Kaposi sarcoma associated herpesvirus pathogenesis (KSHV)--an update.

Authors:  Dirk P Dittmer; Blossom Damania
Journal:  Curr Opin Virol       Date:  2013-06-13       Impact factor: 7.090

Review 6.  Tumour viruses and innate immunity.

Authors:  Sharon E Hopcraft; Blossom Damania
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2017-10-19       Impact factor: 6.237

7.  A comprehensive pathway map of IL-18-mediated signalling.

Authors:  D A B Rex; Nupur Agarwal; T S Keshava Prasad; Richard K Kandasamy; Yashwanth Subbannayya; Sneha M Pinto
Journal:  J Cell Commun Signal       Date:  2019-12-20       Impact factor: 5.782

Review 8.  Human lung-on-chips: Advanced systems for respiratory virus models and assessment of immune response.

Authors:  Ecem Saygili; Ece Yildiz-Ozturk; Macauley J Green; Amir M Ghaemmaghami; Ozlem Yesil-Celiktas
Journal:  Biomicrofluidics       Date:  2021-03-23       Impact factor: 2.800

9.  The NLRP3 Inflammasome and IL-1β Accelerate Immunologically Mediated Pathology in Experimental Viral Fulminant Hepatitis.

Authors:  Sheng Guo; Chengying Yang; Bo Diao; Xiaoyong Huang; Meihua Jin; Lili Chen; Weiming Yan; Qin Ning; Lixin Zheng; Yuzhang Wu; Yongwen Chen
Journal:  PLoS Pathog       Date:  2015-09-14       Impact factor: 6.823

Review 10.  Innate Immunity and Biomaterials at the Nexus: Friends or Foes.

Authors:  Susan N Christo; Kerrilyn R Diener; Akash Bachhuka; Krasimir Vasilev; John D Hayball
Journal:  Biomed Res Int       Date:  2015-07-12       Impact factor: 3.411
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