Literature DB >> 22581232

Plasticity and banking potential of cultured adipose tissue derived mesenchymal stem cells.

M Dhanasekaran1, S Indumathi, R Poojitha, A Kanmani, J S Rajkumar, D Sudarsanam.   

Abstract

The present day research on stem cells is yet not filled to the gunwales. The correlation of stem cell technology with tissue repair still has a long way to go. Since Embryonic stem cells are a kind of thorn inside when it comes to therapeutics, there emerged few potent contemporary sources of stem cells. Though bone marrow proves to be the pioneer among these, they lose themselves to adipose tissue in various aspects. The major shortcoming of bone marrow lies in lieu of its loss in potency with age. Adipose tissue puts up a tough competition among leading edge stem cell sources like cord blood and cord matrix. Adipose tissue wins over its counterparts in that it possesses astounding proliferation potency in vitro and holds a prominent stand in showcasing in vivo tissue repair efficacy. In spite of its precedence, the whole enchilada of adipose derived stem cells is still in its salad days. In our work we aim at excogitating the Mesenchymal stem cell population present in cultured adipose derived stem cells, in a wide perspective. Furthermore, the coalition of cell adhesion molecules with the proliferation potency of MSC and analysis of growth curve of ADSC was also paid accolade. The presence of robust MSC with immense differentiation and transdifferentiation potency was endorsed by lucrative differentiation of P3 cells into mesodermal and neuronal lineages. Additionally, mesenchymal stem cells exhibiting coherent expression of surface markers at P3 in all samples can be cryopreserved for therapeutic applications.

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Year:  2012        PMID: 22581232     DOI: 10.1007/s10561-012-9311-7

Source DB:  PubMed          Journal:  Cell Tissue Bank        ISSN: 1389-9333            Impact factor:   1.522


  7 in total

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4.  Successful isolation of viable adipose-derived stem cells from human adipose tissue subject to long-term cryopreservation: positive implications for adult stem cell-based therapeutics in patients of advanced age.

Authors:  Sean M Devitt; Cynthia M Carter; Raia Dierov; Scott Weiss; Robert P Gersch; Ivona Percec
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5.  Human adult stem cells maintain a constant phenotype profile irrespective of their origin, Basal media, and long term cultures.

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Journal:  Stem Cells Int       Date:  2015-01-20       Impact factor: 5.443

6.  Morphology-based noninvasive early prediction of serial-passage potency enhances the selection of clone-derived high-potency cell bank from mesenchymal stem cells.

Authors:  Takashi Suyama; Yuto Takemoto; Hiromi Miyauchi; Yuko Kato; Yumi Matsuzaki; Ryuji Kato
Journal:  Inflamm Regen       Date:  2022-10-02

7.  Comparative Analysis of the Different Dyes' Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium.

Authors:  I A Zlatskiy; A V Zlatska; N V Antipova; S A Dolenko; I M Gordiienko; O S Gubar; R G Vasyliev; D A Zubov; S N Novikova; A V Syroeshkin
Journal:  ScientificWorldJournal       Date:  2020-02-25
  7 in total

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