Literature DB >> 22581226

Early detection of HIV infection among Kenyan infants using a reverse transcriptase activity assay.

Sumathi Sivapalasingam1, Aabid Ahmed, Megan Mendillo, Robert Holzman, Fatuma Marshed, Musa Mwamzuka, Samuel Khamadi, Matilu Mwau, Maura Laverty, Fred Valentine.   

Abstract

Two hundred HIV-exposed Kenyan infants were tested for HIV infection at birth and at age 6, 12, 24 and 48 weeks, by DNA polymerase chain reaction (PCR) and Cavidi reverse transcriptase (RT) assays and after age 18 months by HIV antibody test. Eleven (5.5%) infants became HIV infected. In 6 infants, positive RT preceded positive DNA PCR. The use of RT assay may facilitate earlier HIV diagnosis in infants.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22581226      PMCID： PMC3405543          DOI： 10.1097/INF.0b013e318259bc1e

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  12 in total

1.  Early detection of perinatal human immunodeficiency virus (HIV) type 1 infection using HIV RNA amplification and detection. New York City Perinatal HIV Transmission Collaborative Study.

Authors:  R W Steketee; E J Abrams; D M Thea; T M Brown; G Lambert; S Orloff; J Weedon; M Bamji; E E Schoenbaum; J Rapier; M L Kalish
Journal:  J Infect Dis       Date:  1997-03       Impact factor: 5.226

2.  Human immunodeficiency virus (HIV) reverse transcriptase activity correlates with HIV RNA load: implications for resource-limited settings.

Authors:  Sumathi Sivapalasingam; Shaffiq Essajee; Phillipe N Nyambi; Vincenza Itri; Bruce Hanna; Robert Holzman; Fred Valentine
Journal:  J Clin Microbiol       Date:  2005-08       Impact factor: 5.948

3.  Simple, sensitive, and specific detection of human immunodeficiency virus type 1 subtype B DNA in dried blood samples for diagnosis in infants in the field.

Authors:  I A Beck; K D Drennan; A J Melvin; K M Mohan; A M Herz; J Alarcón; J Piscoya; C Velázquez; L M Frenkel
Journal:  J Clin Microbiol       Date:  2001-01       Impact factor: 5.948

4.  Viral load and CD4+ T-cell dynamics in primary HIV-1 subtype C infection.

Authors:  Vladimir Novitsky; Elias Woldegabriel; Lemme Kebaabetswe; Raabya Rossenkhan; Busisiwe Mlotshwa; Caitlin Bonney; Mariel Finucane; Rosemary Musonda; Sikhulile Moyo; Carolyn Wester; Erik van Widenfelt; Joseph Makhema; Stephen Lagakos; M Essex
Journal:  J Acquir Immune Defic Syndr       Date:  2009-01-01       Impact factor: 3.731

5.  Quantitation of human immunodeficiency virus type 1 viral load in plasma using reverse transcriptase activity assay at a district hospital laboratory in Botswana: a decentralization pilot study.

Authors:  Madisa Mine; Keabetswe Bedi; Talkmore Maruta; Dignity Madziva; Modiri Tau; Tatenda Zana; Tendani Gaolathe; Sikhulile Moyo; Khumo Seipone; Ndwapi Ndwapi; Max Essex; Richard Marlink
Journal:  J Virol Methods       Date:  2009-03-20       Impact factor: 2.014

6.  Assessment of the low-cost Cavidi ExaVir Load assay for monitoring HIV viral load in pediatric and adult patients.

Authors:  Vicki Greengrass; Barbera Lohman; Lisa Morris; Megan Plate; Pauline M Steele; Judd L Walson; Suzanne M Crowe
Journal:  J Acquir Immune Defic Syndr       Date:  2009-11-01       Impact factor: 3.731

7.  A reverse transcriptase assay for early diagnosis of infant HIV infection in resource-limited settings.

Authors:  Sumathi Sivapalasingam; Usha Patel; Vincenza Itri; Maura Laverty; Kishorchandra Mandaliya; Fred Valentine; Shaffiq Essajee
Journal:  J Trop Pediatr       Date:  2007-06-11       Impact factor: 1.165

Review 8.  Diagnosis of HIV-1 infection in children younger than 18 months in the United States.

Authors:  Jennifer S Read
Journal:  Pediatrics       Date:  2007-12       Impact factor: 7.124

9.  Dynamics and constraints of early infant diagnosis of HIV infection in Rural Kenya.

Authors:  Amin S Hassan; Erick M Sakwa; Helen M Nabwera; Miriam M Taegtmeyer; Robert M Kimutai; Eduard J Sanders; Ken K Awuondo; Maureen N Mutinda; Catherine S Molyneux; James A Berkley
Journal:  AIDS Behav       Date:  2012-01

10.  Monitoring virologic responses to antiretroviral therapy in HIV-infected adults in Kenya: evaluation of a low-cost viral load assay.

Authors:  Sumathi Sivapalasingam; Beatrice Wangechi; Fatuma Marshed; Maura Laverty; Shaffiq Essajee; Robert S Holzman; Fred Valentine
Journal:  PLoS One       Date:  2009-08-28       Impact factor: 3.240
View more
  2 in total

1.  Performance and usability of Cepheid GeneXpert HIV-1 qualitative and quantitative assay in Kenya.

Authors:  Priska Bwana; Joshua Ageng'o; Matilu Mwau
Journal:  PLoS One       Date:  2019-03-22       Impact factor: 3.240

Review 2.  Point-of-care tests detecting HIV nucleic acids for diagnosis of HIV-1 or HIV-2 infection in infants and children aged 18 months or less.

Authors:  Eleanor A Ochodo; Fatuma Guleid; Jonathan J Deeks; Sue Mallett
Journal:  Cochrane Database Syst Rev       Date:  2021-08-12
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.